Molecular characteristics of the capsid protein VP2 gene of canine parvovirus type 2 amplified from raccoon dogs in Hebei province, China
| العنوان: | Molecular characteristics of the capsid protein VP2 gene of canine parvovirus type 2 amplified from raccoon dogs in Hebei province, China |
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| المؤلفون: | Deng Xiaoyu, Yongle Yu, Weiquan Liu, Yang Wang, Qiumei Shi, Hao Liu, Lian Shizhen, Xijun Yan, Xiangyu Zhu, Shuang Lv, Yan Minghao, Hang Zhao, Lu Rongguang, Shi Ning, Hu Bo, Jigui Wang |
| المصدر: | Archives of Virology. 165:2453-2459 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | China, Parvovirus, Canine, animal diseases, viruses, Parvoviridae Infections, 03 medical and health sciences, Virology, Animals, Amino Acid Sequence, Peptide sequence, 030304 developmental biology, 0303 health sciences, biology, Phylogenetic tree, 030306 microbiology, Parvovirus, Canine parvovirus, Subclade, General Medicine, Raccoon Dogs, biology.organism_classification, Capsid, Capsid Proteins, Nyctereutes procyonoides |
| الوصف: | Canine parvovirus type 2 (CPV-2) is currently circulating in domestic and wild animals, but our knowledge about CPV-2 infections in raccoon dogs is limited. In this study, VP2 gene sequences of CPV-2 were amplified from rectal swabs of 14 diarrhetic raccoon dogs (Nyctereutes procyonoides) in Hebei province, China, in 2016 and 2017. Phylogenetic analysis of the VP2 gene sequences revealed that most of these sequences (11 of 14) belonged to the same subclade as raccoon dog strain CPV-2/Raccoon_Dog/China/DP-1/16 isolated from Shandong province in 2016. A comparison of deduced amino acid sequences revealed presence of the substitutions S297A and S27T in 11 of those 14 sequences. I418T was observed in a minority of the sequences (4 of 14). In addition, A300D and T301I, P13S and I219V, and N419K were found in three of the sequences. This study shows that CPV-2 strains with different substitutions in their VP2 amino acid sequences were spreading among raccoon dogs in Hebei during 2016 and 2017 and suggests that further studies are needed to monitor the distribution of these strains in China. |
| تدمد: | 1432-8798 0304-8608 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4979dd9d490470c63a8308a2762a77e5 https://doi.org/10.1007/s00705-020-04714-3 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....4979dd9d490470c63a8308a2762a77e5 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14328798 03048608 |
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