Complete Genomic Structure of the Bloom-forming Toxic Cyanobacterium Microcystis aeruginosa NIES-843
| العنوان: | Complete Genomic Structure of the Bloom-forming Toxic Cyanobacterium Microcystis aeruginosa NIES-843 |
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| المؤلفون: | Mitsuyo Kohara, Shinobu Okamoto, Yoshimi Shimizu, Takakazu Kaneko, Akiko Watanabe, Shinobu Nakayama, Nobuyoshi Nakajima, Naomi Nakazaki, Makoto Watanabe, Yuuhiko Tanabe, Yoshie Kishida, Midori Katoh, Yasukazu Nakamura, Satoshi Tabata, Fumie Kasai, Tsunakazu Fujishiro, Akiko Ono, Kumiko Kawashima, Masanori Tamaoki, Manabu Yamada, Chika Takahashi, Iwane Suzuki, Chiharu Minami |
| المصدر: | DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes |
| بيانات النشر: | Oxford University Press (OUP), 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Transposable element, Microcystis, microcystin, RNase P, genome sequence, Molecular Sequence Data, Biology, Genome, Bacterial Proteins, cyanobacterium, M. aeruginosa, Gene density, Genetics, Insertion sequence, Molecular Biology, Gene, Base Composition, Base Sequence, Sequence Analysis, DNA, General Medicine, Genome project, Full Papers, Protein Structure, Tertiary, Multigene Family, water bloom, Genome, Bacterial, GC-content |
| الوصف: | The nucleotide sequence of the complete genome of a cyanobacterium, Microcystis aeruginosa NIES-843, was determined. The genome of M. aeruginosa is a single, circular chromosome of 5 842 795 base pairs (bp) in length, with an average GC content of 42.3%. The chromosome comprises 6312 putative protein-encoding genes, two sets of rRNA genes, 42 tRNA genes representing 41 tRNA species, and genes for tmRNA, the B subunit of RNase P, SRP RNA, and 6Sa RNA. Forty-five percent of the putative protein-encoding sequences showed sequence similarity to genes of known function, 32% were similar to hypothetical genes, and the remaining 23% had no apparent similarity to reported genes. A total of 688 kb of the genome, equivalent to 11.8% of the entire genome, were composed of both insertion sequences and miniature inverted-repeat transposable elements. This is indicative of a plasticity of the M. aeruginosa genome, through a mechanism that involves homologous recombination mediated by repetitive DNA elements. In addition to known gene clusters related to the synthesis of microcystin and cyanopeptolin, novel gene clusters that may be involved in the synthesis and modification of toxic small polypeptides were identified. Compared with other cyanobacteria, a relatively small number of genes for two component systems and a large number of genes for restriction-modification systems were notable characteristics of the M. aeruginosa genome. |
| تدمد: | 1756-1663 1340-2838 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be32c4cfa5cfc62f83dcf12cadbfb35 https://doi.org/10.1093/dnares/dsm026 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....4be32c4cfa5cfc62f83dcf12cadbfb35 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17561663 13402838 |
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