Data from subjects receiving intrathecal laronidase for cervical spinal stenosis due to mucopolysaccharidosis type I
| العنوان: | Data from subjects receiving intrathecal laronidase for cervical spinal stenosis due to mucopolysaccharidosis type I |
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| المؤلفون: | Alla Victoroff, Patricia I. Dickson, Paul Harmatz, Anton Mlikotic, Ilkka Kaitila, Merry Passage, Agnes Chen, Jacqueline Madden, Steven Q. Le, David E. Naylor |
| المساهمون: | Medicum, Department of Medical and Clinical Genetics |
| المصدر: | Data in Brief, Vol 5, Iss C, Pp 71-76 (2015) Data in Brief |
| بيانات النشر: | Elsevier, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, education, lcsh:Computer applications to medicine. Medical informatics, Pulmonary function testing, 03 medical and health sciences, Mucopolysaccharidosis type I, 0302 clinical medicine, Cerebrospinal fluid, medicine, Adverse effect, lcsh:Science (General), Data Article, 0303 health sciences, Multidisciplinary, medicine.diagnostic_test, business.industry, 030302 biochemistry & molecular biology, Cervical spinal stenosis, Magnetic resonance imaging, Spinal cord, medicine.disease, 3. Good health, medicine.anatomical_structure, Somatosensory evoked potential, Anesthesia, lcsh:R858-859.7, 3111 Biomedicine, business, 030217 neurology & neurosurgery, lcsh:Q1-390 |
| الوصف: | Five subjects with mucopolysaccharidosis type I and symptomatic cervical spinal stenosis received intrathecal laronidase in a 4-month pilot study and/or a 12-month extension study [1]. Clinical descriptions of study subjects, nonserious adverse events, individual data tables, and scoring system methods are provided. There were ten nonserious adverse events that occurred in more than one study subject. Somatosensory evoked potentials were absent in two subjects and normal in two subjects, limiting their utility as an endpoint. There were no significant changes in magnetic resonance imaging of cervical spinal cord or brain, pulmonary function tests, or cerebrospinal fluid opening pressure. These data are presented along with the scoring methods used in evaluation of the study subjects. |
| اللغة: | English |
| تدمد: | 2352-3409 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501580982505211460a492ece22b94d9 http://www.sciencedirect.com/science/article/pii/S2352340915001602 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....501580982505211460a492ece22b94d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23523409 |
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