Magnetic Targeting of mTHPC To Improve the Selectivity and Efficiency of Photodynamic Therapy
| العنوان: | Magnetic Targeting of mTHPC To Improve the Selectivity and Efficiency of Photodynamic Therapy |
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| المؤلفون: | Elina Haimov-Talmoud, Rachela Popovtzer, Menachem Motiei, Orit Shefi, Jean-Paul Lellouche, Yifat Harel, Ayelet Atkins, Hadas Schori |
| المصدر: | ACS Applied Materials & Interfaces. 11:45368-45380 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Programmed cell death, Materials science, medicine.medical_treatment, 030303 biophysics, Biocompatible Materials, Photodynamic therapy, 02 engineering and technology, Ferric Compounds, Magnetics, Mice, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, polycyclic compounds, medicine, Animals, Humans, natural sciences, General Materials Science, Magnetite Nanoparticles, Cell Proliferation, 0303 health sciences, Photosensitizing Agents, Singlet oxygen, Cancer, Cerium, 021001 nanoscience & nanotechnology, medicine.disease, Xenograft Model Antitumor Assays, eye diseases, Mesoporphyrins, Photochemotherapy, chemistry, Drug delivery, Cancer research, 0210 nano-technology, Selectivity, therapeutics |
| الوصف: | Photodynamic therapy (PDT) is a promising recognized treatment for cancer. To date, PDT drugs are injected systemically, and the tumor area is irradiated to induce cell death. Current clinical protocols have several drawbacks, including limited accessibility to solid tumors and insufficient selectivity of drugs. Herein, we propose an alternative approach to improve PDT effectiveness by magnetic targeting of responsive carriers conjugated to the PDT drug. We coordinatively attached a |
| تدمد: | 1944-8252 1944-8244 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105f118579f2c62887519d15175b247 https://doi.org/10.1021/acsami.9b14060 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....5105f118579f2c62887519d15175b247 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 19448252 19448244 |
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