Methotrexate loaded alginate microparticles and effect of Ca2+ post-crosslinking: An in vitro physicochemical and biological evaluation

التفاصيل البيبلوغرافية
العنوان: Methotrexate loaded alginate microparticles and effect of Ca2+ post-crosslinking: An in vitro physicochemical and biological evaluation
المؤلفون: Rohit Srivastava, Chaitra Shetty, Mukesh Dhanka
المصدر: International Journal of Biological Macromolecules. 110:294-307
بيانات النشر: Elsevier BV, 2018.
سنة النشر: 2018
مصطلحات موضوعية: SUSTAINED-RELEASE, Biocompatibility, INTERNAL GELATION, Nanotechnology, 02 engineering and technology, Chemical interaction, Microparticles, 010402 general chemistry, 01 natural sciences, Biochemistry, CONTROLLED DRUG-DELIVERY, Structural Biology, POLYMER MICROPARTICLES, SUSPENSION-ENHANCED DISPERSION, medicine, HYBRID PARTICLES, Fourier transform infrared spectroscopy, Molecular Biology, Biological evaluation, W/O EMULSIFICATION, Chemistry, Alginate, General Medicine, 021001 nanoscience & nanotechnology, In vitro, RHEUMATOID-ARTHRITIS, 0104 chemical sciences, SUPERCRITICAL CO2, Solvent, Methotrexate, Emulsion, 0210 nano-technology, SURFACE TEXTURES, medicine.drug, Nuclear chemistry
الوصف: Methotrexate (MTX) loaded alginate microparticles were produced by simple water-in-oil (W/O) emulsion solvent diffusion method with homogenization and then subsequently cross-linked by Ca2+. The mean sizes of developed microparticles (bare non-crosslinked, crosslinked, drug-loaded non-crosslinked, and drug-loaded cross-linked) were found to be
تدمد: 0141-8130
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d2426269f07549422bcc78f90f0f64
https://doi.org/10.1016/j.ijbiomac.2017.10.148
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....51d2426269f07549422bcc78f90f0f64
قاعدة البيانات: OpenAIRE