Comparing the Safety and Efficacy of Microwave Ablation Using ThermosphereTM Technology versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Propensity Score-Matched Analysis
| العنوان: | Comparing the Safety and Efficacy of Microwave Ablation Using ThermosphereTM Technology versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Propensity Score-Matched Analysis |
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| المؤلفون: | Takayoshi Oikawa, Hiroki Sato, Kei Endo, Yudai Fujiwara, Hidekatsu Kuroda, Yohei Kooka, Tamami Abe, Kei Sawara, Tomoaki Nagasawa, Yasuhiro Takikawa |
| المصدر: | Cancers Volume 13 Issue 6 Cancers, Vol 13, Iss 1295, p 1295 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, Radiofrequency ablation, medicine.medical_treatment, lcsh:RC254-282, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Overall survival, Medicine, Single lesion, business.industry, Microwave ablation, hepatocellular carcinoma, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Ablation, Oncology, microwave ablation, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Propensity score matching, 030211 gastroenterology & hepatology, radiofrequency ablation, Radiology, business |
| الوصف: | There is limited information regarding the oncological benefits of microwave ablation using ThermosphereTM technology for hepatocellular carcinoma. This study compared the overall survival and recurrence-free survival outcomes among patients with hepatocellular carcinoma after microwave ablation using ThermosphereTM technology and after radiofrequency ablation. Between December 2017 and August 2020, 410 patients with hepatocellular carcinoma (a single lesion that was ≤5 cm or ≤3 lesions that were ≤3 cm) underwent ablation at our institution. Propensity score matching identified 150 matched pairs of patients with well-balanced characteristics. The microwave ablation and radiofrequency ablation groups had similar overall survival rates at 1 year (99.3% vs. 98.2%) and at 2 years (88.4% vs. 87.5%) (p = 0.728), as well as similar recurrence-free survival rates at 1 year (81.1% vs. 76.2%) and at 2 years (60.5% vs. 62.1%) (p = 0.492). However, the microwave ablation group had a significantly lower mean number of total insertions (1.22 ± 0.49 vs. 1.59 ± 0.94 p < 0.0001). This retrospective study revealed no significant differences in the overall survival and recurrence-free survival outcomes after microwave ablation or radiofrequency ablation. However, we recommend microwave ablation for hepatocellular carcinoma tumors with a diameter of > 2 cm based on the lower number of insertions. |
| وصف الملف: | application/pdf |
| تدمد: | 2072-6694 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ec5eb485fb7a72b08ceb4a00a8cb93 https://doi.org/10.3390/cancers13061295 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....52ec5eb485fb7a72b08ceb4a00a8cb93 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726694 |
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