التفاصيل البيبلوغرافية
| العنوان: |
CCR 20th Anniversary Commentary: Determining a Pharmacokinetic/Pharmacodynamic Relationship for Sunitinib—A Look Back |
| المؤلفون: |
A. Douglas Laird, Julie M. Cherrington, Dirk B. Mendel |
| المصدر: |
Clinical cancer research : an official journal of the American Association for Cancer Research. 21(11) |
| سنة النشر: |
2015 |
| مصطلحات موضوعية: |
Oncology, Cancer Research, medicine.medical_specialty, Indoles, business.industry, Pharmacokinetic pharmacodynamic, Sunitinib, Pharmacology, History, 21st Century, Clinical trial, Anniversaries and Special Events, Internal medicine, Receptor tyrosine kinase inhibitor, Neoplasms, Medicine, Humans, Pyrroles, business, medicine.drug |
| الوصف: |
The article by Mendel and colleagues, published in the January 1, 2003, issue of Clinical Cancer Research, described their novel preclinical approach to developing a thorough understanding of the exposure–activity relationship for sunitinib, a multitargeted receptor tyrosine kinase inhibitor being developed for oncology therapy. This work successfully set exposure guidelines to identify a biologically active dose in early clinical trials. Clin Cancer Res; 21(11); 2415–7. ©2015 AACR. See related article by Mendel et al., Clin Cancer Res 2003;9(1) January 2003;327–37 |
| تدمد: |
1557-3265 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dae8bc98399632d01d35ac4e7acd94
https://pubmed.ncbi.nlm.nih.gov/26034217 |
| رقم الأكسشن: |
edsair.doi.dedup.....53dae8bc98399632d01d35ac4e7acd94 |
| قاعدة البيانات: |
OpenAIRE |
