Myofibroblast Transformation in Metastatic Extramedullary Chronic Myeloid Leukemia: A Case Report
| العنوان: | Myofibroblast Transformation in Metastatic Extramedullary Chronic Myeloid Leukemia: A Case Report |
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| المؤلفون: | Bing-Yu Mao, Tianxiang Pang, Qinghua Li, Yong-Xin Ru, Brian P Eyden, En-Bin Liu |
| المصدر: | Ultrastructural Pathology. 33:136-140 |
| بيانات النشر: | Informa UK Limited, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, Myocytes, Smooth Muscle, Disease, Pathology and Forensic Medicine, Microscopy, Electron, Transmission, Stroma, Recurrence, Structural Biology, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Humans, Medicine, Organelles, business.industry, Melanoma, Myeloid leukemia, Fibroblasts, Middle Aged, medicine.disease, Peripheral blood, Lymphoma, Leukemia, Cell Transformation, Neoplastic, Disease Progression, Female, Lymph Nodes, sense organs, business, Myofibroblast |
| الوصف: | Primary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers. |
| تدمد: | 1521-0758 0191-3123 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54263ee12aad91bd9e8f45f135a88561 https://doi.org/10.1080/01913120902786961 |
| رقم الأكسشن: | edsair.doi.dedup.....54263ee12aad91bd9e8f45f135a88561 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15210758 01913123 |
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