Organ-sparing surgery of the bilateral testicular large cell calcifying sertoli cell tumor in patient with atypical Peutz–Jeghers syndrome
| العنوان: | Organ-sparing surgery of the bilateral testicular large cell calcifying sertoli cell tumor in patient with atypical Peutz–Jeghers syndrome |
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| المؤلفون: | W. Cichy, A. Plawski, B. S. Lipska, A. Gintowt, A. Kaluzny, Marcin Matuszewski, K. Krajka, S. Wojtylak |
| المصدر: | International Urology and Nephrology |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, Pathology, medicine.medical_specialty, Urology, Peutz-Jeghers Syndrome, STK11, Peutz–Jeghers syndrome, Protein Serine-Threonine Kinases, Testicle, Large cell calcifying sertoli cell tumor, Diagnosis, Differential, Young Adult, AMP-Activated Protein Kinase Kinases, Testicular Neoplasms, Calcinosis, medicine, Organ-sparing testicular surgery, Humans, Carney complex, business.industry, Nucleic acid amplification technique, medicine.disease, medicine.anatomical_structure, Nephrology, Sertoli Cell Tumor, Urology – Case Report, Differential diagnosis, STK11 amplification, business, Nucleic Acid Amplification Techniques, Orchiectomy |
| الوصف: | Large cell calcifying sertoli cell tumor (LCCSCT) is an exceptionally rare neoplasm originating from sperm cord cells. The tumors have relatively low malignant potential and unlikely proceed to metastasis formation. The lesions may occur in an isolated form or in ca. 40% of cases may be associated with genetic abnormalities, by and large Peutz-Jeghers syndrome and Carney complex. At presentation, 20% of LCCSCT cases are bilateral and/or multifocal. Owning to characteristic skin lesions and particular hyperechoic ultrasound image of the tumor, preliminary diagnosis of the syndromic LCCSCT is possible in the preoperative period. Consequently, testicle organ-sparing procedure can be attempted, which is especially justified in bilateral lesions. Here, we report a case of a bilateral LCCSCT in a 20-year-old man with atypical Peutz-Jeghers syndrome due to amplification of the exon 1 of STK11 gene who was successfully treated with bilateral testicle-sparing tumorectomies. |
| تدمد: | 1573-2584 0301-1623 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b7eb6f55eb43291e8527b3475da317 https://doi.org/10.1007/s11255-011-0100-1 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....55b7eb6f55eb43291e8527b3475da317 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15732584 03011623 |
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