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Adaptive step size algorithm to increase efficiency of proton macro Monte Carlo dose calculation

التفاصيل البيبلوغرافية
العنوان: Adaptive step size algorithm to increase efficiency of proton macro Monte Carlo dose calculation
المؤلفون: Werner Volken, R. Kueng, Peter Manser, Daniel Frei, Fabian Stuermlin, Daniel M. Aebersold, Michael K. Fix, Marco Stampanoni
المصدر: Radiation Oncology, 14 (1)
Radiation Oncology, Vol 14, Iss 1, Pp 1-11 (2019)
Küng, Reto; Frei, Daniel; Volken, Werner; Stuermlin, Fabian; Stampanoni, Marco F M; Aebersold, Daniel M.; Manser, Peter; Fix, Michael K. (2019). Adaptive step size algorithm to increase efficiency of proton macro Monte Carlo dose calculation. Radiation oncology, 14(1), p. 165. BioMed Central 10.1186/s13014-019-1362-5 <http://dx.doi.org/10.1186/s13014-019-1362-5>
Radiation Oncology (London, England)
بيانات النشر: Springer Science and Business Media LLC, 2019.
سنة النشر: 2019
مصطلحات موضوعية: Organs at Risk, lcsh:Medical physics. Medical radiology. Nuclear medicine, lcsh:R895-920, Monte Carlo method, 610 Medicine & health, lcsh:RC254-282, 030218 nuclear medicine & medical imaging, k-nearest neighbors algorithm, 03 medical and health sciences, 0302 clinical medicine, Proton transport, Perpendicular, Humans, Medicine, Macro Monte Carlo, Radiology, Nuclear Medicine and imaging, Radiometry, Proton therapy, Dose calculation, Phantoms, Imaging, business.industry, Radiotherapy Planning, Computer-Assisted, Research, Radiotherapy Dosage, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Pencil (optics), Oncology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Slab, business, Monte Carlo Method, Algorithm, Algorithms, Order of magnitude
الوصف: Purpose To provide fast and accurate dose calculation in voxelized geometries for proton radiation therapy by implementing an adaptive step size algorithm in the proton macro Monte Carlo (pMMC) method. Methods The in-house developed local-to-global MMC method for proton dose calculation is extended with an adaptive step size algorithm for efficient proton transport through a voxelized geometry by sampling transport parameters from a pre-simulated database. Adaptive choice of an adequate slab size in dependence of material interfaces in the proton’s longitudinal and lateral vicinity is investigated. The dose calculation algorithm is validated against the non-adaptive pMMC and full MC simulation for pencil and broad beams with various energies impinging on academic phantoms as well as a head and neck patient CT. Results For material interfaces perpendicular to a proton’s direction, choice of nearest neighbor slab thickness shows best trade-off between dosimetric accuracy and calculation efficiency. Adaptive reduction of chosen slab size is shown to be required for material interfaces closer than 0.5 mm in lateral direction. For the academic phantoms, dose differences of within 1% or 1 mm compared to full Geant4 MC simulation are found, while achieving an efficiency gain of up to a factor of 5.6 compared to the non-adaptive algorithm and 284 compared to Geant4. For the head and neck patient CT, dose differences are within 1% or 1 mm with an efficiency gain factor of up to 3.4 compared to the non-adaptive algorithm and 145 compared to Geant4. Conclusion An adaptive step size algorithm for proton macro Monte Carlo was implemented and evaluated. The dose calculation provides the accuracy of full MC simulations, while achieving an efficiency gain factor of three compared to the non-adaptive algorithm and two orders of magnitude compared to full MC for a complex patient CT.
Radiation Oncology, 14 (1)
وصف الملف: application/application/pdf; application/pdf
تدمد: 1748-717X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bc8b23caf2c87638e21b73ee01ae4c
https://doi.org/10.1186/s13014-019-1362-5
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....55bc8b23caf2c87638e21b73ee01ae4c
قاعدة البيانات: OpenAIRE
الوصف
تدمد:1748717X