Bacteriological Profile in Septicaemic Patients with Elevated C-reactive Protein in Intensive Care Units at A Tertiary Care Hospital

التفاصيل البيبلوغرافية
العنوان: Bacteriological Profile in Septicaemic Patients with Elevated C-reactive Protein in Intensive Care Units at A Tertiary Care Hospital
المؤلفون: S.R. Hariharan, K.V. Leela, S.R. Manjula, A. Gomathi Chitra, A. Karthik
المصدر: Journal of Pure and Applied Microbiology, Vol 15, Iss 4, Pp 2034-2040 (2021)
بيانات النشر: Journal of Pure and Applied Microbiology, 2021.
سنة النشر: 2021
مصطلحات موضوعية: medicine.medical_specialty, intensive care units, business.industry, Tertiary care hospital, bacteriological profile, Applied Microbiology and Biotechnology, Microbiology, QR1-502, Elevated C-reactive protein, sepsis, resistance, antibiogram, c-reactive protein, Intensive care, Emergency medicine, medicine, business, Biotechnology
الوصف: Sepsis, the second leading cause of death is due to infections. Intensive care units (ICUs) are having the highest burden of treating the patients with sepsis and nosocomial infections compared to other areas of hospitals. Our objective was to identify the bacteriological profile and their antibiogram of sepsis cases in all ICUs. A sum of 102 blood samples were collected from patients with clinically suspected sepsis with elevated CRP. Processed by an automated method using Bact/Alert & growth were identified by Standard guidelines. Out of 102 samples, 54 (53%) were shown positive by culture. Gram-negative bacilli were the predominant and their number were 33 (61.1% ) and the commonest organisms were from the Enterobacteriaceae family. Escherichia coli was the highest number with 15 (27.7%) followed by Klebsiella pneumoniae 10 (18.51%), & the rest were single isolates of Salmonella typhi, Proteus mirabilis and Citrobacter koseri. Nonfermenter isolated were Acinetobacter baumanii 3 (5.6%), Pseudomonas aeruginosa 2 (3.7%). The Gram-positive cocci were 17 & 32.4% of culture positivity. Coagulase-negative Staphylococcus was the highest isolated accounting for 9 (16.6%) followed by Staphylococcus aureus 6 (11.1%) and Enterococcus faecalis (3.7%). Culture positivity will be more when CRP is also included in the selection of samples for sepsis and Gram-negative bacilli are the leading cause in septicemia and organisms belonging to the Enterobacteriaceae family still dominate in septicemia infections in ICUs and a real challenge for treatment are MDRs which needs to be detected regularly by using screening tests.
تدمد: 2581-690X
0973-7510
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ff832634afb6ec70c84f39b9507023
https://doi.org/10.22207/jpam.15.4.25
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....56ff832634afb6ec70c84f39b9507023
قاعدة البيانات: OpenAIRE