Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus
| العنوان: | Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus |
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| المؤلفون: | Renata Leite, S C L Van Winden, C. Febraro, Liam Good, Juliano Leonel Gonçalves, Marcos Veiga dos Santos, D. Craig, A. Buanz |
| المصدر: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP JDS Communications |
| بيانات النشر: | American Dairy Science Association, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Biguanide, medicine.drug_class, Antimicrobial, medicine.disease_cause, medicine.disease, Sodium dichloroisocyanurate, RS, Mastitis, Microbiology, chemistry.chemical_compound, Chlorhexidine digluconate, chemistry, POLÍMEROS (QUÍMICA ORGÂNICA), Staphylococcus aureus, medicine, RG |
| الوصف: | Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB nanoparticles (NP) against mastitis-causing Staph. aureus using a microdilution assay methodology. A total of 20 mastitis-causing Staph. aureus isolates were used to determine the minimum inhibitory concentrations (MIC) of PHMB and PHMB NP compared with 3 disinfectants commonly used for teat disinfection (chlorhexidine digluconate, povidone-iodine, and sodium dichloroisocyanurate). The MIC90 was defined at the concentrations required to inhibit the growth of 90% of Staph. aureus. Our results indicated that PHMB NP presented the lowest MIC value ( |
| وصف الملف: | application/pdf |
| تدمد: | 2666-9102 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fe39c0d538655edf45a8c6fcb50bfd https://doi.org/10.3168/jdsc.2021-0114 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....57fe39c0d538655edf45a8c6fcb50bfd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26669102 |
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