Adjuvant intravenous immunoglobulin administration on postoperative critically ill patients with secondary peritonitis: a retrospective study
| العنوان: | Adjuvant intravenous immunoglobulin administration on postoperative critically ill patients with secondary peritonitis: a retrospective study |
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| المؤلفون: | Young Un Choi, Jun Gi Kim, Ji Young Jang, Tae Hwa Go, Kwangmin Kim, Keum Seok Bae, Hongjin Shim |
| المصدر: | Acute and Critical Care. 38:21-30 |
| بيانات النشر: | The Korean Society of Critical Care Medicine, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Critical Care and Intensive Care Medicine, Critical Care Nursing |
| الوصف: | Background: The use of intravenous immunoglobulin (IVIG) in sepsis patients from bowel perforation is still debatable. However, few studies have evaluated the effect of IVIG as an adjuvant therapy after source control. This study aimed to analyze the effect of IVIG in critically ill patients who underwent surgery due to secondary peritonitis. Methods: In total, 646 medical records of surgical patients who were treated for secondary peritonitis were retrospectively analyzed. IVIG use, initial clinical data, and changes in Sequential Organ Failure Assessment (SOFA) score over the 7-day admission in the intensive care unit for sepsis check, base excess, and delta neutrophil index (DNI) were analyzed. Mortalities and periodic profiles were assessed. Propensity scoring matching as comparative analysis was performed in the IVIG group and non-IVIG group. Results: General characteristics were not different between the two groups. The survival curve did not show a significantly reduced mortality in the IVIG. Moreover, the IVIG group did not have a lower risk ratio for mortality than the non-IVIG group. However, when the DNI were compared during the first 7 days, the reduction rate in the IVIG group was statistically faster than in the non-IVIG group (P |
| تدمد: | 2586-6060 2586-6052 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59268e0d5c329096ef62797903d8da3e https://doi.org/10.4266/acc.2022.01515 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....59268e0d5c329096ef62797903d8da3e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25866060 25866052 |
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