Adult respiratory distress syndrome after treatment with pegylated interferon α-2a and ribavirin

التفاصيل البيبلوغرافية
العنوان: Adult respiratory distress syndrome after treatment with pegylated interferon α-2a and ribavirin
المؤلفون: Edmond Vartany, Cary Caldwell, Terence K. Trow
المصدر: Heart & Lung. 37:153-156
بيانات النشر: Elsevier BV, 2008.
سنة النشر: 2008
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, ARDS, medicine.medical_specialty, Multiple Organ Failure, Fulminant, Interferon alpha-2, Critical Care and Intensive Care Medicine, Antiviral Agents, Gastroenterology, Polyethylene Glycols, Sepsis, chemistry.chemical_compound, Fatal Outcome, Interferon, Pegylated interferon, Internal medicine, Ribavirin, medicine, Humans, Respiratory Distress Syndrome, Respiratory distress, business.industry, Interferon-alpha, Hepatitis C, Middle Aged, medicine.disease, Recombinant Proteins, chemistry, Immunology, Female, Cardiology and Cardiovascular Medicine, business, medicine.drug
الوصف: Pulmonary manifestations of interferon (IFN) use are a rare but well known complication seen with both standard and pegylated interferon alpha-2b (pegIFNalpha-2b) forms of the agent. These are generally of modest intensity and reversible. We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure. Practicing gastroenterologists and intensivists alike need to be aware of the potential for serious pulmonary sequelae with the use of combination therapy for chronic hepatitis C viral (CHCV) infections.
تدمد: 0147-9563
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5937aff0826317e96bcd6fe23b802f63
https://doi.org/10.1016/j.hrtlng.2007.10.002
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....5937aff0826317e96bcd6fe23b802f63
قاعدة البيانات: OpenAIRE