American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020
| العنوان: | American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020 |
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| المؤلفون: | Kristin Higgins, Charles B. Simone, Benjamin Movsas, Larry L. Kestin, Jessica S. Donington, Andrea S. Wolf, Igor I. Rybkin, Arya Amini, Indrin J. Chetty, Stephen G. Chun, Martin J. Edelman, George Rodrigues, Joe Y. Chang, Ben J. Slotman, Kenneth E. Rosenzweig |
| المساهمون: | Radiation Oncology, CCA - Cancer Treatment and quality of life |
| المصدر: | Journal of Thoracic Oncology, 16(1), 66-75. International Association for the Study of Lung Cancer Chun, S G, Simone, C B, Amini, A, Chetty, I J, Donington, J, Edelman, M J, Higgins, K A, Kestin, L L, Movsas, B, Rodrigues, G B, Rosenzweig, K E, Slotman, B J, Rybkin, I I, Wolf, A & Chang, J Y 2021, ' American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020 ', Journal of Thoracic Oncology, vol. 16, no. 1, pp. 66-75 . https://doi.org/10.1016/j.jtho.2020.10.020 |
| بيانات النشر: | Elsevier BV, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Context (language use), Appropriate Use Criteria, Limited stage SCLC, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Combined Modality Therapy, Lung cancer, Intensive care medicine, business.industry, Chemoradiotherapy, medicine.disease, Small Cell Lung Carcinoma, United States, respiratory tract diseases, Clinical trial, Radiation therapy, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cranial Irradiation, Prophylactic cranial irradiation, business, Radium |
| الوصف: | Introduction Combined modality therapy with concurrent chemotherapy and radiation has long been the standard of care for limited-stage SCLC (LS-SCLC). However, there is controversy over best combined modality practices for LS-SCLC. To address these controversies, the American Radium Society (ARS) Thoracic Appropriate Use Criteria (AUC) Committee have developed updated consensus guidelines for the treatment of LS-SCLC. Methods The ARS AUC are evidence-based guidelines for specific clinical conditions that are reviewed by a multidisciplinary expert panel. The guidelines include a review and analysis of current evidence with application of consensus methodology (modified Delphi) to rate the appropriateness of treatments recommended by the panel for LS-SCLC. Agreement or consensus was defined as less than or equal to 3 rating points from the panel median. The consensus ratings and recommendations were then vetted by the ARS Executive Committee and subject to public comment before finalization. Results The ARS Thoracic AUC committee developed multiple consensus recommendations for LS-SCLC. There was strong consensus that patients with unresectable LS-SCLC should receive concurrent chemotherapy with radiation delivered either once or twice daily. For medically inoperable T1-T2N0 LS-SCLC, either concurrent chemoradiation or stereotactic body radiation followed by adjuvant chemotherapy is a reasonable treatment option. The panel continues to recommend whole-brain prophylactic cranial irradiation after response to chemoradiation for LS-SCLC. There was panel agreement that prophylactic cranial irradiation with hippocampal avoidance and programmed cell death protein-1/programmed death-ligand 1–directed immune therapy should not be routinely administered outside the context of clinical trials at this time. Conclusions The ARS Thoracic AUC Committee provide consensus recommendations for LS-SCLC that aim to provide a groundwork for multidisciplinary care and clinical trials. |
| تدمد: | 1556-0864 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a2f429c5d73cd9279c6e98af36ddaf https://doi.org/10.1016/j.jtho.2020.10.020 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....59a2f429c5d73cd9279c6e98af36ddaf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15560864 |
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