Primary Spinal Epidural Mantle Cell Lymphoma: Case Report
| العنوان: | Primary Spinal Epidural Mantle Cell Lymphoma: Case Report |
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| المؤلفون: | Maja Barnard, Bayardo Perez-Ordonez, Lee Cyn Ang, David W. Rowed |
| المصدر: | Neurosurgery. 47:1239-1242 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, medicine.medical_treatment, Lymphoma, Mantle-Cell, Diagnosis, Differential, Spinal cord compression, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aged, medicine.diagnostic_test, business.industry, Lymphoma, Non-Hodgkin, Laminectomy, Lumbosacral Region, Magnetic resonance imaging, medicine.disease, Combined Modality Therapy, Magnetic Resonance Imaging, Epidural space, Lymphoma, Surgery, Radiation therapy, medicine.anatomical_structure, Spinal decompression, Mantle cell lymphoma, Epidural Neoplasms, Neurology (clinical), business |
| الوصف: | OBJECTIVE AND IMPORTANCE Mantle cell lymphoma is a distinct clinicopathological type of non-Hodgkin's lymphoma that often presents at an advanced stage, with systemic spread. Spinal involvement is uncommon and generally occurs as part of advanced disease or generalized relapses. Primary spinal epidural lymphoma is a rare initial manifestation of non-Hodgkin's lymphoma, and mantle cell lymphoma with initial presentation in the spinal epidural space is extremely rare, having been previously reported in only two cases. CLINICAL PRESENTATION We report a case of a 71-year-old man who presented with increasing weakness and numbness of the legs. Magnetic resonance imaging revealed a spinal epidural mass in the lumbosacral region. INTERVENTION The patient underwent a partial L4 and L5–S1 laminectomy, with incomplete resection of the mass for spinal decompression and tissue diagnosis. Mantle cell lymphoma was diagnosed in the pathological examination. CONCLUSION After radiotherapy, the disease recurred with a soft-tissue mass in the anterior maxillary area of the face. The patient underwent restaging and was treated with chemotherapy, with only a partial response. Mantle cell lymphoma with primary spinal epidural presentation is rare. This diagnosis can be established and other causes of spinal cord compression can be ruled out by obtaining tissue for proper histopathological examinations. Because of its aggressive behavior and poor prognosis, mantle cell lymphoma should be treated using a combined-modality approach. |
| تدمد: | 1524-4040 0148-396X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a56ba69c03290ef8a543dee75d3291 https://doi.org/10.1097/00006123-200011000-00046 |
| رقم الأكسشن: | edsair.doi.dedup.....59a56ba69c03290ef8a543dee75d3291 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244040 0148396X |
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