Clinicopathological characteristics and prognosis of gastric cancer with malignant ascites

التفاصيل البيبلوغرافية
العنوان: Clinicopathological characteristics and prognosis of gastric cancer with malignant ascites
المؤلفون: Shan Lu, Yi-Ye Wan, Mei Xie, Nong-Rong Wang, Bo He, Hui-Qing Zhang, Nian Fang
المصدر: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 35(4)
سنة النشر: 2013
مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Poor prognosis, Adolescent, medicine.medical_treatment, Treatment plan, Stomach Neoplasms, Internal medicine, Ascites, medicine, Humans, Survival rate, Aged, Retrospective Studies, Aged, 80 and over, Chemotherapy, ECOG Score, Helicobacter pylori, business.industry, Cancer, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Prognosis, Female, medicine.symptom, business
الوصف: Management of gastric cancer with malignant ascites is a challenge, and limited data are available. We evaluated factors affecting survival for this condition to determine factors that predict survival outcome and to develop a rational treatment plan. We retrospectively studied 5,542 patients with gastric adenocarcinoma from January 2007 to December 2012. Among them, 347 patients (6.26 %) were associated with malignant ascites. The patients’ overall survival was compared among the different features. Three hundred forty-seven patients (153 females and 194 males; median age, 53 years) were enrolled, including 78 (22.5 %) young patients and 63 (18.1 %) elderly patients. One hundred forty-three (41.2 %) patients presented with malignant ascites at the initial diagnosis of gastric cancer, and 211 (60.8 %) received chemotherapy. After a median follow-up duration of 10.4 months, the median survival after the diagnosis of malignant ascites was 5.2 months (95 % CI, 4.8–5.6 months), and the 1-year survival rate was 16.1 %. An ECOG score greater than 2 (P
تدمد: 1423-0380
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b70f2a186659ddf0ca8cc5d8a7db494
https://pubmed.ncbi.nlm.nih.gov/24282088
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....5b70f2a186659ddf0ca8cc5d8a7db494
قاعدة البيانات: OpenAIRE