Biocompatibility of a chlorhexidine local delivery system in a subcutaneous mouse model
| العنوان: | Biocompatibility of a chlorhexidine local delivery system in a subcutaneous mouse model |
|---|---|
| المؤلفون: | Adriana Socorro Ferreira Monteiro, Luís Guilherme Scavone de Macedo, Nelson Luiz de Macedo, Thiago Toyoshima, Fernanda Alves Feitosa |
| المساهمون: | Universidade Estadual Paulista (Unesp) |
| المصدر: | Monteiro, Adriana Socorro Ferreira ; Macedo, Luís Guilherme Scavone ; Macedo, Nelson Luiz ; Feitosa, Fernanda Alves ; Toyoshima, Thiago. Biocompatibility of a chlorhexidine local delivery system in a subcutaneous mouse model. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 2 2011: 27 RODERIC. Repositorio Institucional de la Universitat de Valéncia instname Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, Biocompatibility, Dentistry, Biocompatible Materials, chlorhexidine toxicity, Mice, Drug Delivery Systems, Subcutaneous Tissue, parasitic diseases, medicine, drug delivery system, Animals, Rats, Wistar, periodontitis, General Dentistry, Periodontitis, business.industry, Chlorhexidine, CIENCIAS MÉDICAS [UNESCO], medicine.disease, Biocompatible material, Rats, Otorhinolaryngology, Models, Animal, UNESCO::CIENCIAS MÉDICAS, Anti-Infective Agents, Local, Surgery, Delivery system, business, medicine.drug |
| الوصف: | Made available in DSpace on 2013-08-12T19:11:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-03-01 Made available in DSpace on 2013-09-30T18:34:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-03-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:04:50Z No. of bitstreams: 0 Made available in DSpace on 2014-05-20T14:04:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-03-01 Objective: This study aimed evaluating histologically and histomorphometrically the response of the conjunctive tissue face to the implant of chlorhexidine chips in the subcutaneous tissues of rats. Study Design: In this research 35 male rats Wistar were used to analyze the biocompatibility and the degradation process of chlorhexidine chip. In each animal, it was made 2 incisions for subcutaneous implantation of chlorhexidine chip (test group) and a polytetrafluorethylene membrane (control group). The morphological changes in subcutaneous implantations were assessed after 1, 3, 5, 7, 10, 14, 21 days. The data were submitted to Friedman nonparametric test to analyze the comparisons among observation periods and to allow the comparison among groups. Results: Differences were found in the analysis of the inflammatory response when comparing the tested materials (p values |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b887a2e1396405cd16abda8f624717a http://hdl.handle.net/10550/60172 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....5b887a2e1396405cd16abda8f624717a |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |