Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling
| العنوان: | Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling |
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| المؤلفون: | Francisco B. Rodriguez, Pablo Varona, Angel Lareo, Reynaldo D. Pinto, Caroline Garcia Forlim |
| المساهمون: | UAM. Departamento de Ingeniería Informática, Neurocomputación Biológica (ING EPS-005) |
| المصدر: | Frontiers in Neuroinformatics Frontiers in Neuroinformatics, Vol 10 (2016) Biblos-e Archivo. Repositorio Institucional de la UAM instname Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Neuroinformatics, Signal processing, Information theory, Computer science, Biomedical Engineering, Neuroscience (miscellaneous), Context (language use), Electric fish, computer.software_genre, electric fish, lcsh:RC321-571, Computational biology, 03 medical and health sciences, 0302 clinical medicine, Software, computational biology, Methods, TEORIA DA INFORMAÇÃO, signal processing, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, information theory, Informática, Communication, business.industry, Information processing, neuroinformatics, Toolbox, Computer Science Applications, 030104 developmental biology, Data mining, business, computer, 030217 neurology & neurosurgery, Neuroscience |
| الوصف: | This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permission Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox. This work was funded by Spanish projects of Ministerio de Economia y Competitividad/FEDER TIN-2010-19607, TIN2014-54580-R, TIN-2012-30883, DPI2015 65833-P (http://www.mineco.gob.es/), ONRG grant N62909-14-1-N279, Brazilian Agency of Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (http://www.cnpq.br/) and Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (www.fapesp.br). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
| وصف الملف: | application/pdf |
| تدمد: | 1662-5196 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb237b37e6c5b59bf6a70c54700373c https://pubmed.ncbi.nlm.nih.gov/27766078 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....5bb237b37e6c5b59bf6a70c54700373c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16625196 |
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