Ass's milk in children with atopic dermatitis and cow's milk allergy: Crossover comparison with goat's milk
| العنوان: | Ass's milk in children with atopic dermatitis and cow's milk allergy: Crossover comparison with goat's milk |
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| المؤلفون: | Giovanni Battista Pajno, Giovanni Passalacqua, D. Vita, Imma Rulli, Giuseppe Crisafulli, Giuseppe Di Pasquale, Lucia Caminiti |
| المصدر: | Pediatric Allergy and Immunology. 18:594-598 |
| بيانات النشر: | Wiley, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Male, Allergy, Visual analogue scale, Immunology, ass's milk, Dermatitis, Atopic, law.invention, Atopy, fluids and secretions, Animal science, Randomized controlled trial, law, Food allergy, Immune Tolerance, medicine, Animals, Humans, Immunology and Allergy, Skin Tests, Cross-Over Studies, atopic dermatitis, goat's milk, business.industry, Goats, Infant, food and beverages, Equidae, Atopic dermatitis, medicine.disease, cow's milk allergy, Crossover study, Milk, Tolerability, Child, Preschool, Pediatrics, Perinatology and Child Health, Electrophoresis, Polyacrylamide Gel, Female, Milk Hypersensitivity, business |
| الوصف: | Cow milk allergy is a common disease of infancy, often associated with atopic dermatitis (AD). Avoidance of cow milk (CM) implies the use of alternative dietary supports such as mammalian milks. In this study, we assessed the tolerability and clinical effect of ass's milk (AM), when compared with the largely used goat's milk (GM) in a single-blind, controlled, randomized crossover. Twenty-eight children with AD and ascertained allergy to CM were enrolled. The children were randomized to AM or GM for 6 months, then switched to the other milk for further 3 months. The SCORAD index (SI) and a visual analog scale (VAS) were evaluated blindly. After termination of the study, food challenges with GM and AM were performed. An SDS-PAGE analysis of different milks was performed. Two children from the GM group dropped out after randomization and 26 completed the study. Ass milk invariantly led to a significant improvement of SI and VAS of symptoms (p < 0.03 vs. baseline and inter-group), whereas GM had no measurable clinical effect. At the end of the study 23 of 26 children had a positive food challenge with GM and one of 26 with AM. Ass's milk had a protein profile closer to human milk than GM. Ass milk is better tolerated and more effective than GM in reducing symptoms of AD. It may represent a better substitute of CM than the currently used GM. |
| تدمد: | 1399-3038 0905-6157 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7043597f5fce9b8999d0f1298dc989 https://doi.org/10.1111/j.1399-3038.2007.00567.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....5c7043597f5fce9b8999d0f1298dc989 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993038 09056157 |
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