Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain
| العنوان: | Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain |
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| المؤلفون: | Rakesh M. Suri, A. Marc Gillinov, Brian P. Griffin, L. Leonardo Rodriguez, Amgad Mentias, Richard A. Grimm, Lars G. Svensson, Alaa Alashi, Tomislav Mihaljevic, Milind Y. Desai, Peyman Naji |
| المصدر: | Cardiovascular Diagnosis and Therapy. 8:460-468 |
| بيانات النشر: | AME Publishing Company, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, Mitral regurgitation, Ejection fraction, business.industry, Odds ratio, 030204 cardiovascular system & hematology, Asymptomatic, Metabolic equivalent, Confidence interval, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Ventricular pressure, Cardiology, Original Article, 030212 general & internal medicine, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Body mass index |
| الوصف: | Background: Despite preserved left ventricular ejection fraction (LVEF), patients with significant primary mitral regurgitation (MR) often have reduced exercise capacity. In asymptomatic patients with ≥3+ primary MR undergoing rest-stress echocardiography (RSE), we sought to evaluate the incremental impact of left ventricular global longitudinal strain (LV-GLS) on exercise capacity. Methods: A total of 660 asymptomatic patients with ≥3+ primary MR, non-dilated LV and LVEF ≥60% (mean age, 57±14 years, 66% men, body mass index or BMI 25±4 kg/m 2 ) who underwent RSE at our center between 2001 and 2013 were included. Standard RSE data were obtained. Average resting LV-GLS was measured using Velocity Vector Imaging. Results: Mean mitral effective regurgitant orifice, resting right ventricular systolic pressure (RVSP) and LV-GLS were 0.45±0.2 cm 2 , 31±12 mmHg and −21.7%±2%, respectively; 28% had flail mitral leaflet. Mean metabolic equivalents (METs) and post-stress RVSP were 9.9±3, and 46±17 mmHg; 28% achieved |
| تدمد: | 2223-3660 2223-3652 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c75a0c06823a72f050a69331c4bc37c https://doi.org/10.21037/cdt.2018.05.03 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....5c75a0c06823a72f050a69331c4bc37c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22233660 22233652 |
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