Pressure from schoolwork is associated with health complaints in primary and high school students. Girls are more likely to report high levels of pressure and experience frequent health complaints. However, the moderating effect of gender on the relationship between pressure and health complaints has not been fully explored. Logistic regression was used to examine the association between pressure from schoolwork and health complaints for a sample of 11–12 and 13–14-year-olds in Australia (N = 4723), England (N = 2734) and Spain (N = 3743), moderating for gender and controlling for family affluence and teacher support. Across the entire sample, a significant relationship between pressure and frequent health complaints was found (OR = 3.03, p