Prevalence of plasma lipid disorders with an emphasis on LDL cholesterol in selected countries in the Asia-Pacific region
العنوان: | Prevalence of plasma lipid disorders with an emphasis on LDL cholesterol in selected countries in the Asia-Pacific region |
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المؤلفون: | Zhen-Vin Lee, Elmer Jasper Llanes, Renan Sukmawan, Nuntakorn Thongtang, Huynh Quang Tri Ho, Philip Barter, on behalf of the Cardiovascular RISk Prevention (CRISP) in Asia Network |
المصدر: | Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-12 (2021) Lipids in Health and Disease |
بيانات النشر: | BMC, 2021. |
سنة النشر: | 2021 |
مصطلحات موضوعية: | Asia, RC620-627, Clinical chemistry, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Lipid Metabolism Disorders, Disease, Clinical nutrition, Review, 030204 cardiovascular system & hematology, Guidelines, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Plasma lipid disorders, Environmental health, Plasma lipids, medicine, Prevalence, Humans, 030212 general & internal medicine, Disease management (health), Nutritional diseases. Deficiency diseases, Hypolipidemic Agents, Ldl cholesterol, Pacific Ocean, business.industry, Biochemistry (medical), Asia-Pacific, Cholesterol, LDL, medicine.disease, Dyslipidemia, Practice Guidelines as Topic, lipids (amino acids, peptides, and proteins), business, Lipidology |
الوصف: | Cardiovascular disease (CVD) is a major cause of mortality and morbidity within the Asia-Pacific region, with the prevalence of CVD risk factors such as plasma lipid disorders increasing in many Asian countries. As members of the Cardiovascular RISk Prevention (CRISP) in Asia network, the authors have focused on plasma lipid disorders in the six countries within which they have clinical experience: Indonesia, Malaysia, Philippines, Thailand, Vietnam, and Australia. Based on country-specific national surveys, the prevalence of abnormal levels of total cholesterol, low- and high-density lipoprotein cholesterol (LDL-C and HDL-C, respectively), and triglycerides (TG) are reported. An important caveat is that countries have used different thresholds to define plasma lipid disorders, making direct comparisons difficult. The prevalence of abnormal lipid levels was as follows: high total cholesterol (30.2–47.7%, thresholds: 190–213 mg/dL); high LDL-C (33.2–47.5%; thresholds: 130–135 mg/dL); low/abnormal HDL-C (22.9–72.0%; thresholds: 39–50 mg/dL); and high/abnormal TG (13.9–38.7%; thresholds: 150–177 mg/dL). Similarities and differences between country-specific guidelines for the management of plasma lipid disorders are highlighted. Based on the authors’ clinical experience, some of the possible reasons for suboptimal management of plasma lipid disorders in each country are described. Issues common to several countries include physician reluctance to prescribe high-dose and/or high-intensity statins and poor understanding of disease, treatments, and side effects among patients. Treatment costs and geographical constraints have also hampered disease management in Indonesia and the Philippines. Understanding the factors governing the prevalence of plasma lipid disorders helps enhance strategies to reduce the burden of CVD in the Asia-Pacific region. |
اللغة: | English |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea65c71325ce6c72497f1341e677b83 https://doaj.org/article/60605ec0c3ec458aa88cb7ff41febbe7 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....5ea65c71325ce6c72497f1341e677b83 |
قاعدة البيانات: | OpenAIRE |
الوصف غير متاح. |