Testosterone therapy and secondary erythrocytosis

التفاصيل البيبلوغرافية
العنوان: Testosterone therapy and secondary erythrocytosis
المؤلفون: Joshua White, Francis Petrella, Jesse Ory
المصدر: International Journal of Impotence Research. 34:693-697
بيانات النشر: Springer Science and Business Media LLC, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Hematocrit, Phlebotomy, Urology, Humans, Testosterone, Polycythemia
الوصف: Secondary erythrocytosis is one of the most common adverse events associated with testosterone therapy (TT). Upon encountering this, clinicians will often either adjust TT dosing, stop therapy, order a phlebotomy, or recommend a combination of these. Despite this, the evidence for secondary polycythemia causing harm during TT is scarce, and the hematocrit-based cutoffs present in multiple guidelines appear to be arbritrarily chosen. In this review, we present the pathophysiology behind TT and secondary erythrocytosis, the evidence connecting TT, secondary erythrocytosis and major adverse cardiovascular events (MACE), and the data supporting varying interventions upon diagnosis of secondary erythrocytosis.
تدمد: 1476-5489
0955-9930
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeacfd8e0b8f26685bcea3d4e8398f6
https://doi.org/10.1038/s41443-021-00509-5
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....5eeacfd8e0b8f26685bcea3d4e8398f6
قاعدة البيانات: OpenAIRE