Testosterone therapy and secondary erythrocytosis
العنوان: | Testosterone therapy and secondary erythrocytosis |
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المؤلفون: | Joshua White, Francis Petrella, Jesse Ory |
المصدر: | International Journal of Impotence Research. 34:693-697 |
بيانات النشر: | Springer Science and Business Media LLC, 2022. |
سنة النشر: | 2022 |
مصطلحات موضوعية: | Hematocrit, Phlebotomy, Urology, Humans, Testosterone, Polycythemia |
الوصف: | Secondary erythrocytosis is one of the most common adverse events associated with testosterone therapy (TT). Upon encountering this, clinicians will often either adjust TT dosing, stop therapy, order a phlebotomy, or recommend a combination of these. Despite this, the evidence for secondary polycythemia causing harm during TT is scarce, and the hematocrit-based cutoffs present in multiple guidelines appear to be arbritrarily chosen. In this review, we present the pathophysiology behind TT and secondary erythrocytosis, the evidence connecting TT, secondary erythrocytosis and major adverse cardiovascular events (MACE), and the data supporting varying interventions upon diagnosis of secondary erythrocytosis. |
تدمد: | 1476-5489 0955-9930 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeacfd8e0b8f26685bcea3d4e8398f6 https://doi.org/10.1038/s41443-021-00509-5 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....5eeacfd8e0b8f26685bcea3d4e8398f6 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14765489 09559930 |
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