Genomic and serological assessment of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in child labor
| العنوان: | Genomic and serological assessment of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in child labor |
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| المؤلفون: | Niloofar Najafi, Hoorieh Soleimanjahi, Shadab Shahali, Mahmoud Reza Pourkarim, Marijn Thijssen, Fatemeh Fotouhi, Taravat Bamdad, Kayhan Azadmanesh, Zeynab Nasiri, Neda Afzali, Mohammad Reza Jabbari, Atefeh Yari, Hesam Karimi, Mohammad Hadi Karbalaei Niya |
| المصدر: | Pathog Glob Health |
| بيانات النشر: | Informa UK Limited, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Adult, Adolescent, SARS-CoV-2, Public Health, Environmental and Occupational Health, COVID-19, Genomics, General Medicine, Antibodies, Viral, Microbiology, Cross-Sectional Studies, Infectious Diseases, Seroepidemiologic Studies, Child, Preschool, Humans, Parasitology, Child, Child Labor, Research Article |
| الوصف: | Since working children have limited access to testing and monitoring for COVID-19, we decided to measure SARS-CoV-2 prevalence among them and compare it to non-working children. Our objective is to compare the frequency of SARS-CoV-2 genome and anti-SARS-CoV-2 antibody among working and non-working children. Volunteer child labor studying at Defense of Child Labor and Street Children and randomly selected 5–18-year-old (same range as child labor group) unemployed children participated in this study. The groups, respectively, had 65 and 137 members. This is an analytical cross-sectional study that surveys molecular prevalence of SARS-CoV-2 infection by RT-PCR, and seroprevalence of SARS-CoV-2 antibody by ELISA in working and non-working children. The IBM SPSS statistics software version 25 was used for data analysis. The χ2 or Fisher’s exact test was used to analyze categorical dependent variables, for calculating odds ratios and 95% confidence intervals. Among the children enrolled in this study, molecular prevalence of SARS-CoV-2 turned out to be 18.5% in working children while it was 5.8% in unemployed children [aOR: 3.00 (CI95%: 1.00–7.00); P value: 0.003] and seroprevalence turned out to be 20% in working children vs 13.9% in non-working children [aOR: 1.000 (CI95%: 0.00–2.00); > P 0.001]. Equal SARS-CoV-2 viral load as adults and no symptoms or mild ones in children, coupled with working children’s strong presence in crowded areas and their higher rate of COVID-19 prevalence, make them a probable source for spread of the virus. |
| تدمد: | 2047-7732 2047-7724 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4e11da2900bf9acff2f5f519248c51 https://doi.org/10.1080/20477724.2022.2038052 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....5f4e11da2900bf9acff2f5f519248c51 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 20477732 20477724 |
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