Influence of Taurine on Cardiac Remodeling Induced by Tobacco Smoke Exposure
| العنوان: | Influence of Taurine on Cardiac Remodeling Induced by Tobacco Smoke Exposure |
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| المؤلفون: | Luiz Shiguero Matsubara, Sergio A. R. Paiva, Ana Paula Lima-Leopoldo, Bertha F. Polegato, Leonardo A. M. Zornoff, Lidiane P. Ardisson, Paula S. Azevedo, Beatriz Bojikian Matsubara, Fabiana Gouveia Denipote, Ethel L. B. Novelli, Marcos F. Minicucci, Fernanda Chiuso-Minicucci |
| المساهمون: | Universidade Estadual Paulista (Unesp) |
| المصدر: | ResearcherID Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| بيانات النشر: | S. Karger AG, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Taurine, Physiology, Heart Ventricles, Heart failure, Tobacco smoke, chemistry.chemical_compound, Smoke, Internal medicine, Lactate dehydrogenase, Tobacco, Heart rate, medicine, Animals, Phosphorylation, Rats, Wistar, Ventricular function, Isovolumetric contraction, L-Lactate Dehydrogenase, Ventricular Remodeling, Chemistry, Calcium-Binding Proteins, Smoking, Tobacco smoke exposure, medicine.disease, Rats, Phospholamban, Endocrinology, Echocardiography |
| الوصف: | Made available in DSpace on 2013-09-27T14:54:30Z (GMT). No. of bitstreams: 1 WOS000290594900013.pdf: 985087 bytes, checksum: e8d3ad68a7bd4c88c546df17eb21e0b5 (MD5) Previous issue date: 2011-01-01 Made available in DSpace on 2013-09-30T18:40:55Z (GMT). No. of bitstreams: 1 WOS000290594900013.pdf: 985087 bytes, checksum: e8d3ad68a7bd4c88c546df17eb21e0b5 (MD5) Previous issue date: 2011-01-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:50:53Z No. of bitstreams: 1 WOS000290594900013.pdf: 985087 bytes, checksum: e8d3ad68a7bd4c88c546df17eb21e0b5 (MD5) Made available in DSpace on 2014-05-20T13:50:53Z (GMT). No. of bitstreams: 1 WOS000290594900013.pdf: 985087 bytes, checksum: e8d3ad68a7bd4c88c546df17eb21e0b5 (MD5) Previous issue date: 2011-01-01 Background/Aims: To investigate the effect of taurine on cardiac remodeling induced by smoking. Methods: In the first step, rats were allocated into two groups: Group C (n=14): control; Group T (n=14): treated with taurine (3% in drinking water), for three months. In the second step, rats were allocated into two groups: Group ETS (n=9): rats exposed to tobacco smoke; Group ETS-T (n=9): rats exposed to tobacco smoke and treated with taurine for two months. Results: After three months, taurine presented no effects on morphological or functional variables of normal rats assessed by echocardiogram. on the other hand, after two months, ETS-T group presented higher LV wall thickness (ETS=1.30 (1.20-1.42); ETS-T=1.50 (1.40-1.50); p=0.029), E/A ratio (ETS=1.13 +/- 0.13; ETS-T=1.37 +/- 0.26; p=0.028), and isovolumetric relaxation time normalized for heart rate (ETS=53.9 +/- 4.33; ETS-T=72.5 +/- 12.0; p |
| تدمد: | 1421-9778 1015-8987 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7a5c9e231f2e59fac9e84b896d842d https://doi.org/10.1159/000327955 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....5f7a5c9e231f2e59fac9e84b896d842d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219778 10158987 |
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