Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review
العنوان: | Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review |
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المؤلفون: | Jeanette Dawa, Y-Ling Chi, Nuru Saadi, Srobana Ghosh, Anna Vassall, Ciara V McCarthy, Matthew Quaife, Rosalind M Eggo, Mark Jit |
المصدر: | BMC Medicine medRxiv BMC Medicine, Vol 19, Iss 1, Pp 1-11 (2021) |
سنة النشر: | 2021 |
مصطلحات موضوعية: | Adult, medicine.medical_specialty, COVID-19 Vaccines, COVID-19, Vaccination, Mathematical modelling, Population, Review, EconLit, 03 medical and health sciences, 0302 clinical medicine, Environmental health, 0502 economics and business, Epidemiology, Medicine, Humans, 030212 general & internal medicine, education, 030304 developmental biology, 0303 health sciences, education.field_of_study, business.industry, SARS-CoV-2, Public health, 05 social sciences, Vaccination, COVID-19, General Medicine, 3. Good health, Economic evaluation, Portfolio, 050211 marketing, Public Health, business, Inclusion (education) |
الوصف: | Background How best to prioritise COVID-19 vaccination within and between countries has been a public health and an ethical challenge for decision-makers globally. We reviewed epidemiological and economic modelling evidence on population priority groups to minimise COVID-19 mortality, transmission, and morbidity outcomes. Methods We searched the National Institute of Health iSearch COVID-19 Portfolio (a database of peer-reviewed and pre-print articles), Econlit, the Centre for Economic Policy Research, and the National Bureau of Economic Research for mathematical modelling studies evaluating the impact of prioritising COVID-19 vaccination to population target groups. The first search was conducted on March 3, 2021, and an updated search on the LMIC literature was conducted from March 3, 2021, to September 24, 2021. We narratively synthesised the main study conclusions on prioritisation and the conditions under which the conclusions changed. Results The initial search identified 1820 studies and 36 studies met the inclusion criteria. The updated search on LMIC literature identified 7 more studies. 43 studies in total were narratively synthesised. 74% of studies described outcomes in high-income countries (single and multi-country). We found that for countries seeking to minimise deaths, prioritising vaccination of senior adults was the optimal strategy and for countries seeking to minimise cases the young were prioritised. There were several exceptions to the main conclusion, notably that reductions in deaths could be increased if groups at high risk of both transmission and death could be further identified. Findings were also sensitive to the level of vaccine coverage. Conclusion The evidence supports WHO SAGE recommendations on COVID-19 vaccine prioritisation. There is, however, an evidence gap on optimal prioritisation for low- and middle-income countries, studies that included an economic evaluation, and studies that explore prioritisation strategies if the aim is to reduce overall health burden including morbidity. |
وصف الملف: | application/pdf |
تدمد: | 1741-7015 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd523f589f4430e548b877fd59ee9d3 https://pubmed.ncbi.nlm.nih.gov/34847950 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....5fd523f589f4430e548b877fd59ee9d3 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 17417015 |
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