Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen
| العنوان: | Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen |
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| المؤلفون: | Paul Sundberg, Mary Thurn, Paulo Lages, Poonam Dubey, Jamie Henningson, Kent Schwartz, Giovani Trevisan, Eric R. Burrough, Eric Herrman, Jon Greseth, Leticia Linhares, Gregg Hanzlicek, Bret Crim, Daniel Linhares, Jane Christopher-Hennings, Rodger Main, Cesar Corzo, Ram K. Raghavan, Travis Clement, Douglas Marthaler, Jerry Torrison |
| المصدر: | PLoS ONE PLoS ONE, Vol 14, Iss 10, p e0223544 (2019) |
| بيانات النشر: | Public Library of Science, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Veterinary medicine, Swine, animal diseases, Population Dynamics, Infographics, Geographical locations, 0403 veterinary science, Genotype, Geography, Medical, Mammals, 0303 health sciences, Disease reporting, Multidisciplinary, Data Processing, biology, Eukaryota, Agriculture, 04 agricultural and veterinary sciences, Clinical Laboratory Services, Veterinary Diagnostics, Charts, Veterinary Diseases, Vertebrates, Medicine, Information Technology, Research Article, Veterinary Medicine, Computer and Information Sciences, Livestock, 040301 veterinary sciences, Science, Porcine Reproductive and Respiratory Syndrome, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, 03 medical and health sciences, Animals, Porcine respiratory and reproductive syndrome virus, Population Biology, 030306 microbiology, Data Visualization, Organisms, Biology and Life Sciences, Porcine reproductive and respiratory syndrome virus, biology.organism_classification, Laboratories, Hospital, United States, Geographic Distribution, Geographic distribution, Amniotes, North America, Oral fluid, Veterinary Science, People and places, Merge (version control) |
| الوصف: | This project investigates the macroepidemiological aspects of porcine reproductive and respiratory syndrome virus (PRRSV) RNA detection by veterinary diagnostic laboratories (VDLs) for the period 2007 through 2018. Standardized submission data and PRRSV real-time reverse-transcriptase polymerase chain reaction (RT-qPCR) test results from porcine samples were retrieved from four VDLs representing 95% of all swine samples tested in NAHLN laboratories in the US. Anonymized data were retrieved and organized at the case level using SAS (SAS® Version 9.4, SAS® Institute, Inc., Cary, NC) with the use of PROC DATA, PROC MERGE, and PROC SQL scripts. The final aggregated and anonymized dataset comprised of 547,873 unique cases was uploaded to Power Business Intelligence-Power BI® (Microsoft Corporation, Redmond, Washington) to construct dynamic charts. The number of cases tested for PRRSV doubled from 2010 to 2018, with that increase mainly driven by samples typically used for monitoring purposes rather than diagnosis of disease. Apparent seasonal trends for the frequency of PRRSV detection were consistently observed with a higher percentage of positive cases occurring during fall or winter months and lower during summer months, perhaps due to increased testing associated with well-known seasonal occurrence of swine respiratory disease. PRRSV type 2, also known as North American genotype, accounted for 94.76% of all positive cases and was distributed across the US. PRRSV type 1, also known as European genotype, was geographically restricted and accounted for 2.15% of all positive cases. Co-detection of both strains accounted for 3.09% of the positive cases. Both oral fluid and processing fluid samples, had a rapid increase in the number of submissions soon after they were described in 2008 and 2017, respectively, suggesting rapid adoption of these specimens by the US swine industry for PRRSV monitoring in swine populations. As part of this project, a bio-informatics tool defined as Swine Disease Reporting System (SDRS) was developed. This tool has real-time capability to inform the US swine industry on the macroepidemiological aspects of PRRSV detection, and is easily adaptable for other analytes relevant to the swine industry. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fd55c7a090e8e48bacab4a5f11a23d http://europepmc.org/articles/PMC6795434 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....60fd55c7a090e8e48bacab4a5f11a23d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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