Small volume biopsy diagnostic yield at initial diagnosis versus recurrence/transformation of follicular lymphoma: A retrospective Cyto‐Heme Interinstitutional Collaborative study
| العنوان: | Small volume biopsy diagnostic yield at initial diagnosis versus recurrence/transformation of follicular lymphoma: A retrospective Cyto‐Heme Interinstitutional Collaborative study |
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| المؤلفون: | Megan J. Fitzpatrick, Vandana Sundaram, Amy Ly, Jeremy S. Abramson, Ronald Balassanian, Matthew C. Cheung, Stephen L. Cook, Lorenzo Falchi, Annabel K. Frank, Srishti Gupta, Robert P. Hasserjian, Oscar Lin, Steven R. Long, Joshua R. Menke, Eric Mou, Daniel R. Reed, Roberto Ruiz‐Cordero, Ashley K. Volaric, Linlin Wang, Kwun Wah Wen, Yi Xie, Sara L. Zadeh, Dita Gratzinger |
| المصدر: | Cancer Cytopathology. 131:279-288 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cancer Research, Oncology |
| الوصف: | Few studies have evaluated diagnostic yield of small volume biopsies (SVB) for the diagnosis and management of follicular lymphoma (FL).The authors performed a multi-institutional retrospective analysis of SVBs including fine-needle aspiration (FNA) and needle core biopsy (NCB) for initial FL diagnosis and suspected recurrence or transformation of FL. A total of 676 workups beginning with SVB were assessed for the mean number of biopsies per workup, the proportion of workups requiring multiple biopsies, and the proportion with a complete diagnosis including grade, on initial biopsy.Compared to workups performed for question transformation/recurrence, those done for initial FL diagnosis were significantly more likely to require multiple biopsies (p .01), had a higher mean number of biopsies per workup (1.7 vs. 1.1, absolute standardized difference = 1.1), and a lower complete diagnosis rate at initial biopsy (39% vs. 56%). At initial FL diagnosis, NCB +/- FNA was associated with fewer biopsies per workup compared to FNA +/- CB (1.2 vs. 1.9), fewer workups requiring multiple biopsies (23% vs. 83%), and a higher complete diagnosis rate (71% vs. 18%). In contrast, during assessment for transformation/recurrence, NCB and FNA showed a similar mean number of biopsies per workup (1.2 vs. 1.2) and few workups required multiple biopsies (6% vs. 19%).SVB at initial FL diagnosis often required additional biopsies to establish a complete diagnosis. In contrast, when assessing for transformed/recurrent FL, additional biopsies were generally not obtained regardless of SVB type, suggesting that in these clinical settings SVB may be sufficient for clinical decision-making. |
| تدمد: | 1934-6638 1934-662X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61235393d748b51f1625cba0a2f18598 https://doi.org/10.1002/cncy.22676 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....61235393d748b51f1625cba0a2f18598 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19346638 1934662X |
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