Lymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer
| العنوان: | Lymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer |
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| المؤلفون: | de Jong, Mees Hendrik Siert, Gisbertz, Suzanne Sarah, van Berge Henegouwen, Mark Ivo, Draaisma, Werner Adriaan |
| المساهمون: | Surgery, CCA - Cancer Treatment and quality of life, CCA - Cancer Treatment and Quality of Life, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism |
| المصدر: | de Jong, M H S, Gisbertz, S S, van Berge Henegouwen, M I & Draaisma, W A 2022, ' Lymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer ', Journal of Gastrointestinal Oncology, vol. 13, no. 4, pp. 1605-1615 . https://doi.org/10.21037/jgo-22-147 Journal of Gastrointestinal Oncology, 13(4), 1605-1615. Pioneer Bioscience Publishing Company (PBPC) |
| بيانات النشر: | AME Publishing Company, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | adenocarcinoma, Oncology, Stomach neoplasms, Gastroenterology, neoplasm staging, lymph node excision, gastrectomy |
| الوصف: | Background: The incidence of lymph node metastases is closely related to the T-stage, and therefore Eastern guidelines advice a D1 lymphadenectomy for early gastric cancer and a D2 lymphadenectomy for advanced gastric cancer. The aim of this study was to compare the lymph node metastases rate in the stations dissected with a D2-lymphadenectomy (stations 8-12) yet spared with a D1-lymphadenectomy, between different T-stages in a Western patient cohort. Methods: For this retrospective study, patients who underwent a gastrectomy in the Amsterdam University Medical Center (UMC), location Academic Medical Center (AMC), between 2011 and 2016 were identified from a prospectively maintained database. The primary outcome was to compare the rate of lymph node metastases in station 8-12 between different cT-stages. Results: One hundred twelve patients met our inclusion criteria. There were no positive lymph nodes in the lymph nodes stations 8-12 in cT1 and (y)pT1-stage tumors. The more advanced cT2-4 and (y)pT2-4 stage tumors show a high metastases rate (11.1% to 40.0%) in the lymph node stations 8-12. Conclusions: The results from this study endorse the Japanese Gastric Cancer Guideline; in early gastric cancer, a D1 lymphadenectomy is sufficient, while in advanced gastric cancer a D2 lymphadenectomy should be performed. |
| تدمد: | 2219-679X 2078-6891 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6140080edbf2713c75d384acff4e6796 https://doi.org/10.21037/jgo-22-147 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6140080edbf2713c75d384acff4e6796 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2219679X 20786891 |
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