High Dose Therapy and Autologous Stem Cell Transplantation in Follicular non-Hodgkin's Lymphoma
| العنوان: | High Dose Therapy and Autologous Stem Cell Transplantation in Follicular non-Hodgkin's Lymphoma |
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| المؤلفون: | Lee M. Nadler, John G. Gribben, Arnold S. Freedman |
| المصدر: | Leukemia & Lymphoma. 28:219-230 |
| بيانات النشر: | Informa UK Limited, 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | Oncology, Cancer Research, medicine.medical_specialty, Follicular lymphoma, Disease, Transplantation, Autologous, Disease-Free Survival, Autologous stem-cell transplantation, Recurrence, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Follicular phase, Humans, Medicine, Lymphoma, Follicular, business.industry, Remission Induction, Hematopoietic Stem Cell Transplantation, Hematopoietic stem cell, Hematology, medicine.disease, Combined Modality Therapy, Minimal residual disease, Lymphoma, Surgery, High dose therapy, medicine.anatomical_structure, business |
| الوصف: | Indolent follicular lymphomas are diseases which are generally incurable with conventional therapy. Although patients can survival for prolonged periods, the median duration of first remissions is about 2.5 years, and subsequent remissions progressively shorten with time. High dose therapy with hematopoietic stem cell support leads to prolonged disease-free and overall survival in a subset of patients with aggressive non-Hodgkin's lymphoma. Mounting evidence suggests similar findings for selected patients with indolent follicular non-Hodgkin's lymphoma. Presently it remains unclear as to when this approach should be used, however inferior results have been seen in heavily pretreated patients. In contrast, encouraging results are being reported in patients undergoing such treatment early in the course of their disease. Despite these data, many patients continue to relapse and future investigations now focus on eradication of minimal residual disease. |
| تدمد: | 1029-2403 1042-8194 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620764ce5f0955f7b27b4c460703c81a https://doi.org/10.3109/10428199809092678 |
| رقم الأكسشن: | edsair.doi.dedup.....620764ce5f0955f7b27b4c460703c81a |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 10292403 10428194 |
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