Biodegradation of p-nitrophenol by engineered strain
| العنوان: | Biodegradation of p-nitrophenol by engineered strain |
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| المؤلفون: | Deng Yongdong, Zhang Wenhui, Gao Jianjie, Jing Xu, Zhang Fujian, Rihe Peng, Bo Wang, Yongsheng Tian, Yao Quanhong, Yu Wang |
| المصدر: | AMB Express AMB Express, Vol 11, Iss 1, Pp 1-8 (2021) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | inorganic chemicals, Biophysics, medicine.disease_cause, Microbiology, Applied Microbiology and Biotechnology, Degradation, chemistry.chemical_compound, Nitrophenol, Bioremediation, p-Nitrophenol, Multigene metabolic engineering, medicine, heterocyclic compounds, Escherichia coli, Pollutant, Hydroquinone, Strain (chemistry), E. coli, Biodegradation, QR1-502, enzymes and coenzymes (carbohydrates), Metabolic pathway, chemistry, Biochemistry, Original Article, TP248.13-248.65, Biotechnology |
| الوصف: | p-Nitrophenol (PNP) is an important environmental pollutant and can causes significant environmental and health risks. Compared with the traditional methods, biodegradation is a useful one to completely remove the harmful pollutants from the environment. Here, an engineered strain was first constructed by introducing PNP biodegradation pathway via the hydroquinone (HQ) pathway into Escherichia coli. In the engineered strain BL-PNP, PNP was completely degraded to β-ketoadipate and subsequently enter the metabolites of multiple anabolic pathways. The high tolerance and rapid degradation ability to PNP enable the engineered strain to have the potential to degrade toxic substances. The engineered strain created in this study can be used as a functional strain for bioremediation of PNP and potential toxic intermediates, and the method of assembling aromatic hydrocarbons metabolic pathway can be used to eradicate nitroaromatic pollutants in the environment. Supplementary Information The online version contains supplementary material available at 10.1186/s13568-021-01284-8. |
| تدمد: | 2191-0855 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6257a07a5420e1fd2c9b535f70739272 https://doi.org/10.1186/s13568-021-01284-8 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6257a07a5420e1fd2c9b535f70739272 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 21910855 |
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