Inhibition of zymosan-induced alternative complement pathway activation by concanavalin A
| العنوان: | Inhibition of zymosan-induced alternative complement pathway activation by concanavalin A |
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| المؤلفون: | M C Smith, G B Naff, J Pensky |
| المصدر: | Infection and Immunity. 38:1279-1284 |
| بيانات النشر: | American Society for Microbiology, 1982. |
| سنة النشر: | 1982 |
| مصطلحات موضوعية: | Complement Pathway, Alternative, Immunology, macromolecular substances, Microbiology, Complement factor B, Complement C1, Lectins, Concanavalin A, Humans, Complement Activation, biology, Complement component 2, Zymosan, hemic and immune systems, Complement C3, Complement system, carbohydrates (lipids), Infectious Diseases, Biochemistry, Factor H, Lectin pathway, biology.protein, Alternative complement pathway, Parasitology, CFHR5, Complement Factor B, Research Article, Complement control protein |
| الوصف: | Zymosan, a polysaccharide composed primarily of glucan and mannan residues, activates the complement system through the alternative complement pathway. We showed that zymosan-induced complement activation is inhibited by zymosan-bound lectins with carbohydrate specificities for mannosyl and glycosyl residues. Lectins unable to bind mannosyl or glucosyl residues did not inhibit zymosan-induced complement activation. |
| تدمد: | 1098-5522 0019-9567 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628a89ca014c858dd25599490da522ce https://doi.org/10.1128/iai.38.3.1279-1284.1982 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....628a89ca014c858dd25599490da522ce |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10985522 00199567 |
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