Persistent post-discharge opioid prescribing after traumatic brain injury requiring intensive care unit admission: A cross-sectional study with longitudinal outcome
| العنوان: | Persistent post-discharge opioid prescribing after traumatic brain injury requiring intensive care unit admission: A cross-sectional study with longitudinal outcome |
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| المؤلفون: | Alexander J. Skojec, Lauren K. Dunn, Mark F. Hanak, Tony R. Wang, Caroline Ruminski, Marcel E. Durieux, Siny Tsang, Joyce Chung, Justin D. Palmer, Christopher D. Lacomis, Shenghao Fang, Sarah N. Spangler, Davis G. Taylor, Samantha J Smith, Bhiken I. Naik |
| المصدر: | PLoS ONE, Vol 14, Iss 11, p e0225787 (2019) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Critical Care and Emergency Medicine, Traumatic Brain Injury, Cross-sectional study, NSAIDs, law.invention, 0302 clinical medicine, law, Brain Injuries, Traumatic, Medicine and Health Sciences, Medicine, Antipsychotics, 030212 general & internal medicine, Longitudinal Studies, Practice Patterns, Physicians', Trauma Medicine, Pain, Postoperative, Analgesics, Multidisciplinary, Medical record, Incidence (epidemiology), Incidence, Drugs, Antidepressants, Middle Aged, Intensive care unit, Patient Discharge, Hospitals, Analgesics, Opioid, Hospitalization, Intensive Care Units, Female, Traumatic Injury, medicine.drug, Research Article, medicine.medical_specialty, Traumatic brain injury, Science, Surgical and Invasive Medical Procedures, Drug Prescriptions, 03 medical and health sciences, Intervention (counseling), Humans, Pain Management, Aged, Retrospective Studies, Pharmacology, business.industry, Retrospective cohort study, medicine.disease, Opioid-Related Disorders, Opioids, Health Care, Cross-Sectional Studies, Opioid, Health Care Facilities, Emergency medicine, business, Neurotrauma, 030217 neurology & neurosurgery |
| الوصف: | Traumatic brain injury (TBI) is associated with increased risk for psychological and substance use disorders. The study aim is to determine incidence and risk factors for persistent opioid prescription after hospitalization for TBI. Electronic medical records of patients age ≥ 18 admitted to a neuroscience intensive care unit between January 2013 and February 2017 for an intracranial injury were retrospectively reviewed. Primary outcome was opioid use through 12 months post-hospital discharge. A total of 298 patients with complete data were included in the analysis. The prevalence of opioid use among preadmission opioid users was 48 (87%), 36 (69%) and 22 (56%) at 1, 6 and 12-months post-discharge, respectively. In the opioid naive group, 69 (41%), 24 (23%) and 17 (19%) were prescribed opioids at 1, 6 and 12 months, respectively. Preadmission opioid use (OR 324.8, 95% CI 23.1-16907.5, p = 0.0004) and higher opioid requirements during hospitalization (OR 4.5, 95% CI 1.8-16.3, p = 0.006) were independently associated with an increased risk of being prescribed opioids 12 months post-discharge. These factors may be used to identify and target at-risk patients for intervention. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bafb5dc3bcd293fc38d736430ea90d https://doaj.org/article/853c8fa97fdb4406a85cf8dff4666eac |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....62bafb5dc3bcd293fc38d736430ea90d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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