Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites
| العنوان: | Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites |
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| المؤلفون: | Brad Haltli, Jo Withers, Fabrice Berrué, Sydnor T. Withers, Russell G. Kerr |
| المصدر: | Marine Drugs; Volume 9; Issue 3; Pages: 369-381 Marine Drugs, Vol 9, Iss 3, Pp 369-381 (2011) Marine Drugs |
| بيانات النشر: | Molecular Diversity Preservation International, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | chemical screening, gorgonian coral, Microorganism, Pharmaceutical Science, Marine Biology, 01 natural sciences, Article, Mass Spectrometry, coral-associated bacteria, UPLC/MS, 03 medical and health sciences, Drug Discovery, Animals, 14. Life underwater, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Chromatography, High Pressure Liquid, Invertebrate, Marine biology, Invertebrate host, Biological Products, 0303 health sciences, Bacteria, biology, 010405 organic chemistry, 030306 microbiology, Ecology, Marine invertebrates, Anthozoa, biology.organism_classification, Invertebrates, 0104 chemical sciences, Chemical screening, Rapid identification, lcsh:Biology (General) |
| الوصف: | Marine invertebrates have proven to be a rich source of secondary metabolites. The growing recognition that marine microorganisms associated with invertebrate hosts are involved in the biosynthesis of secondary metabolites offers new alternatives for the discovery and development of marine natural products. However, the discovery of microorganisms producing secondary metabolites previously attributed to an invertebrate host poses a significant challenge. This study describes an efficient chemical screening method utilizing a 96-well plate-based bacterial cultivation strategy to identify and isolate microbial producers of marine invertebrate-associated metabolites. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1660-3397 |
| DOI: | 10.3390/md9030369 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d48e216992c25f32f918c62923906b |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....63d48e216992c25f32f918c62923906b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16603397 |
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| DOI: | 10.3390/md9030369 |