A broad-spectrum sunscreen prevents cumulative damage from repeated exposure to sub-erythemal solar ultraviolet radiation representative of temperate latitudes
| العنوان: | A broad-spectrum sunscreen prevents cumulative damage from repeated exposure to sub-erythemal solar ultraviolet radiation representative of temperate latitudes |
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| المؤلفون: | D. Lombard, C. Bredoux, Sophie Seité, Delphine Compan, Antony R. Young, François Christiaens, Hélène Zucchi, Anny Fourtanier |
| المصدر: | Journal of the European Academy of Dermatology and Venereology. 24:219-222 |
| بيانات النشر: | Wiley, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Sunlight, integumentary system, business.industry, Irradiance, Dermatology, Atmospheric sciences, medicine.disease, Solar irradiance, Skin Diseases, Solar ultraviolet radiation, Broad spectrum, Infectious Diseases, Photoprotection, medicine, Humans, Skin cancer, business, Sunscreening Agents, Ultraviolet radiation |
| الوصف: | Background We have previously shown the detrimental effects of 19 sub-erythemal exposures to daily ultraviolet radiation (DUVR, which mimics non-extreme exposure conditions), delivered over 4 weeks to volunteers. This source had UVA (320-400 nm) to UVB (290–320 nm) irradiance ratio of 25, instead of that close to 10 that is typically the case with solar-simulated radiation (SSR) that represents summer global sunlight with a clear sky and quasi-zenith solar irradiance. Objective Here, we report on an extension of this previous study, in which we evaluated the photoprotection afforded by a broad-spectrum daily-care product with a low–sun protection factor (SPF 8, UVA-PF 7 and 3* rated UVA protection). We assessed cellular and molecular markers of photodamage that are relevant to skin cancer and photoageing. Results This study shows that biological effects of repeated exposure to DUVR can be prevented by a broad-spectrum daily-care product and that the level of protection afforded varies with the studied endpoint. Conclusion Efficient daily UVR protection, as provided by a broad-spectrum daily-care product, is necessary to prevent the ‘silent’ sub-erythemal cumulative effects of UVR from inadvertent sun exposure. |
| تدمد: | 1468-3083 0926-9959 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64836ded04dd55373eee7ae2e6567ebc https://doi.org/10.1111/j.1468-3083.2009.03332.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....64836ded04dd55373eee7ae2e6567ebc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14683083 09269959 |
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