Computed tomography-based three-dimensional dosimetry of intracavitary brachytherapy for cervical cancer
العنوان: | Computed tomography-based three-dimensional dosimetry of intracavitary brachytherapy for cervical cancer |
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المؤلفون: | Yoshio Monzen, Taichi Kurose, Mio Mito, Koichi Wadasaki, Hajime Okazaki |
المصدر: | Japanese Journal of Radiology. 28:740-745 |
بيانات النشر: | Springer Science and Business Media LLC, 2010. |
سنة النشر: | 2010 |
مصطلحات موضوعية: | Adult, medicine.medical_specialty, medicine.medical_treatment, Brachytherapy, Uterine Cervical Neoplasms, Computed tomography, Three dimensional dosimetry, Imaging, Three-Dimensional, medicine, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Radiometry, Aged, Aged, 80 and over, Cervical cancer, medicine.diagnostic_test, business.industry, Radiotherapy Planning, Computer-Assisted, Intracavitary brachytherapy, Radiotherapy Dosage, Middle Aged, medicine.disease, Radiation therapy, Tomography x ray computed, Female, Radiology, Tomography, X-Ray Computed, Nuclear medicine, business |
الوصف: | The aim of this study was to show the results of computed tomography (CT)-based dosimetry of intracavitary brachytherapy for cervical cancer.A total of 20 patients with cervical cancer underwent intracavitary brachytherapy with external beam radiation therapy. The prescribed dose of brachytherapy was 6 Gy per fraction to point A. In every fraction a CT scan was performed after applicator insertion and three-dimensional (3D) dosimetry was done. The tumor dose was evaluated using D90 (the minimum dose delivered to 90% of the volume), and the doses of risk organs were evaluated using D2cc (the minimum dose in the most irradiated 2 cm3 of the volume).The mean D90 for the clinical target volume (CTV) was 7.0 Gy (range 4.8-9.8 Gy). There was a negative correlation between the volume and the D90 for the CTV. The mean D2cc doses for the rectum and bladder were 6.0 Gy (range 3.9-9.0 Gy) and 6.5 Gy 5 Gy 2.9-9.0 Gy), respectively.CT-based 3D dosimetry of intracavitary brachytherapy for cervical cancer was useful for evaluating the doses of the CTV and the organs at risk. In cases with a large CTV, CTV D90 was often lower than the point A dose, and modulation of the prescribed dose might have to be considered. |
تدمد: | 1867-108X 1867-1071 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660501d6bec6a602c5837095b6d8bae9 https://doi.org/10.1007/s11604-010-0504-3 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....660501d6bec6a602c5837095b6d8bae9 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 1867108X 18671071 |
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