Computed tomography-based three-dimensional dosimetry of intracavitary brachytherapy for cervical cancer

التفاصيل البيبلوغرافية
العنوان: Computed tomography-based three-dimensional dosimetry of intracavitary brachytherapy for cervical cancer
المؤلفون: Yoshio Monzen, Taichi Kurose, Mio Mito, Koichi Wadasaki, Hajime Okazaki
المصدر: Japanese Journal of Radiology. 28:740-745
بيانات النشر: Springer Science and Business Media LLC, 2010.
سنة النشر: 2010
مصطلحات موضوعية: Adult, medicine.medical_specialty, medicine.medical_treatment, Brachytherapy, Uterine Cervical Neoplasms, Computed tomography, Three dimensional dosimetry, Imaging, Three-Dimensional, medicine, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Radiometry, Aged, Aged, 80 and over, Cervical cancer, medicine.diagnostic_test, business.industry, Radiotherapy Planning, Computer-Assisted, Intracavitary brachytherapy, Radiotherapy Dosage, Middle Aged, medicine.disease, Radiation therapy, Tomography x ray computed, Female, Radiology, Tomography, X-Ray Computed, Nuclear medicine, business
الوصف: The aim of this study was to show the results of computed tomography (CT)-based dosimetry of intracavitary brachytherapy for cervical cancer.A total of 20 patients with cervical cancer underwent intracavitary brachytherapy with external beam radiation therapy. The prescribed dose of brachytherapy was 6 Gy per fraction to point A. In every fraction a CT scan was performed after applicator insertion and three-dimensional (3D) dosimetry was done. The tumor dose was evaluated using D90 (the minimum dose delivered to 90% of the volume), and the doses of risk organs were evaluated using D2cc (the minimum dose in the most irradiated 2 cm3 of the volume).The mean D90 for the clinical target volume (CTV) was 7.0 Gy (range 4.8-9.8 Gy). There was a negative correlation between the volume and the D90 for the CTV. The mean D2cc doses for the rectum and bladder were 6.0 Gy (range 3.9-9.0 Gy) and 6.5 Gy 5 Gy 2.9-9.0 Gy), respectively.CT-based 3D dosimetry of intracavitary brachytherapy for cervical cancer was useful for evaluating the doses of the CTV and the organs at risk. In cases with a large CTV, CTV D90 was often lower than the point A dose, and modulation of the prescribed dose might have to be considered.
تدمد: 1867-108X
1867-1071
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660501d6bec6a602c5837095b6d8bae9
https://doi.org/10.1007/s11604-010-0504-3
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....660501d6bec6a602c5837095b6d8bae9
قاعدة البيانات: OpenAIRE