Nail changes associated with pigmentary disorders
| العنوان: | Nail changes associated with pigmentary disorders |
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| المؤلفون: | Shikha Bansal, Chander Grover |
| المصدر: | Pigment International, Vol 8, Iss 2, Pp 76-85 (2021) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | integumentary system, melanonychia, General Medicine, Dermatology, systemic disorders, RL1-803, pigmentary disorders, genetic disorders, sense organs, endocrine disorders, nail, skin and connective tissue diseases, drug induced, aids, malignancy |
| الوصف: | Salient nail unit changes serve as pointers toward systemic disease. On similar lines, salient nail changes are associated with pigmentary disorders, and can help toward diagnosis. Nail changes form a part of various physiologic pigmentary changes including racial pigmentation, pregnancy, or neonatal period. At the same time, a number of nail changes can be valuable clues toward disorders of pigmentation associated with genetic syndromes (Laugier–Hunziker syndrome, incontinentia pigmenti, and tuberous sclerosis), endocrine disorders, disorders of metabolism (alkaptonuria), infections (HIV-AIDS), internal malignancies, etc. Nail changes are especially useful if cutaneous pigmentary changes are suspected to be drug-induced based or associated mucosal and/or cutaneous hyperpigmentation. Various drugs that can cause cutaneous pigmentary alterations along with nail changes include cyclophosphamide, adriamycin, vincristine, docetaxel, paclitaxel, carboplatin, psoralens, hydroxyurea, bleomycin, etc. Nail changes are also associated with disorders of hypomelanosis, for example, vitiligo. Pigmentary changes due to endogenous and exogenous pigments are again diagnosable based on the nail changes they induce. This narrative review highlights the importance of nail changes in suspecting and diagnosing various disorders of pigmentation. It also points toward areas which need future research. |
| اللغة: | English |
| تدمد: | 2349-5782 2349-5847 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660d81a9cec16a6f076492251e69e22d http://www.pigmentinternational.com/article.asp?issn=2349-5847;year=2021;volume=8;issue=2;spage=76;epage=85;aulast=Grover |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....660d81a9cec16a6f076492251e69e22d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23495782 23495847 |
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