Quality-of-Life Assessment in Cancer Treatment Protocols: Research Issues in Protocol Development
| العنوان: | Quality-of-Life Assessment in Cancer Treatment Protocols: Research Issues in Protocol Development |
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| المؤلفون: | Bruce D. Cheson, Timothy D. Moore, Mary S. McCabe, Carolyn C. Gotay, Edward L. Korn |
| المصدر: | JNCI Journal of the National Cancer Institute. 84:575-579 |
| بيانات النشر: | Oxford University Press (OUP), 1992. |
| سنة النشر: | 1992 |
| مصطلحات موضوعية: | Protocol (science), Cancer Research, medicine.medical_specialty, End point, business.industry, MEDLINE, Neoplasms therapy, Survival Analysis, Therapeutic trial, Surgery, Cancer treatment, Quality of life (healthcare), Clinical Protocols, Oncology, Risk analysis (engineering), Neoplasms, Quality of Life, medicine, Humans, business, Study planning |
| الوصف: | Background Interest in incorporating quality of life as an end point in clinical studies of cancer treatment has intensified in recent years. Purpose We provide practical suggestions that will assist investigators considering including quality-of-life assessment in phase III therapeutic trials. Methods We discuss issues important in study planning, including quality-of-life definition, priority studies for quality-of-life assessment, eligibility requirements, and design. Conclusions Many of the problems that quality-of-life studies have encountered, from protocol approval to data analysis, could be addressed and alleviated during protocol development. This discussion is intended to assist and stimulate investigators conducting research in this area. |
| تدمد: | 1460-2105 0027-8874 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690fb3c4a609be4c278dbc545ed931dc https://doi.org/10.1093/jnci/84.8.575 |
| رقم الأكسشن: | edsair.doi.dedup.....690fb3c4a609be4c278dbc545ed931dc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602105 00278874 |
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