Figures S1-S10 from Sarcomatoid Renal Cell Carcinoma Has a Distinct Molecular Pathogenesis, Driver Mutation Profile, and Transcriptional Landscape

التفاصيل البيبلوغرافية
العنوان: Figures S1-S10 from Sarcomatoid Renal Cell Carcinoma Has a Distinct Molecular Pathogenesis, Driver Mutation Profile, and Transcriptional Landscape
المؤلفون: Kanishka Sircar, Ken Chen, Kenna Shaw, Gordon Mills, Ignacio Wistuba, Bogdan Czerniak, Marileila Varella-Garcia, Keith Baggerly, Federico Monzon, Christopher Wood, Nizar Tannir, Pheroze Tamboli, Jaime Rodriguez Canales, Chi-Wan Chow, Eric Jonasch, Patricia Trevisan, Fumi Kawakami, Aron Joon, Chad Creighton, Jose Karam, Bo Peng, Tae Beom Kim, Zixing Wang
بيانات النشر: American Association for Cancer Research (AACR), 2023.
سنة النشر: 2023
الوصف: Figure S1. Biphasic histologic components of sarcomatoid renal cell carcinoma. The macrodissected paired epithelioid or carcinomatous (E) and spindled or sarcomatoid (S) components of clear cell RCC (upper panel), Papillary RCC (middle panel), and chromophobe RCC (lower panel). H&E stain, scale bar 200 ï�­m. Figure S2. Sarcomatoid ccRCC shows fewer VHL deletions. (A) Clear cell RCC (H&E stain, scale bar 100 µm) with (B) Fluorescence in situ hybridization (FISH) image showing paired CEN3q signals (green) and a single VHL signal (red). (C) Sarcomatoid ccRCC (H&E stain, scale bar 100 µm) with (D) FISH image showing balanced CEN3q (green) and VHL (red) signals. (E) Box plot showing significantly higher VHL/3q ratios associated with sarcomatoid histology, P
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6996bb58326d1ade2f888a99a5353727
https://doi.org/10.1158/1078-0432.22468044
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....6996bb58326d1ade2f888a99a5353727
قاعدة البيانات: OpenAIRE