Efficacy of Body Weight Reduction on the SGLT2 Inhibitor in People with Type 2 Diabetes Mellitus
| العنوان: | Efficacy of Body Weight Reduction on the SGLT2 Inhibitor in People with Type 2 Diabetes Mellitus |
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| المؤلفون: | Chong Hwa Kim, Yong Hoon Lee, Yu Chang Lee, Jung Eun Lee, Sol Jae Lee, Su Jin Jeong, Hyun A Cho, Young Lee Jung |
| المصدر: | Journal of Obesity & Metabolic Syndrome Journal of Obesity & Metabolic Syndrome, Vol 26, Iss 2, Pp 107-113 (2017) |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, lcsh:Diseases of the endocrine glands. Clinical endocrinology, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Body weight reduction, 030212 general & internal medicine, Dapagliflozin, Adverse effect, Glycemic, lcsh:RC648-665, business.industry, Type 2 Diabetes Mellitus, SGLT2 inhibitor, medicine.disease, Sulfonylurea, Metformin, Renal glucose reabsorption, chemistry, Original Article, business, medicine.drug |
| الوصف: | Background : Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces hyperglycemia and body weight by inhibiting renal glucose reabsorption. However, only a few studies have demonstrated efficacy of dapagliflozin for type 2 diabetic patients in Korea. We evaluated the efficacy and safety of dapagliflozin for Korean type 2 diabetes patients. Methods : This is a retrospective study that included data from 61 patients who received 12 months of dapagliflozin therapy and who visited a single medical center between January 2015 and July 2016. Patients were separated into three groups: dual combination of dapagliflozin and metformin, triple combination of dapagliflozin and metformin with sulfonylurea, or dipeptidyl peptidase IV inhibitors, and quadriple combination of dapagliflozin, metformin, and sulfonylurea with dipeptidyl peptidase IV inhibitors. Patients who achieved ≥5% body weight reduction were classified as responders, and those who achieved |
| تدمد: | 2508-7576 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad95718cd1b211b7a303f3077ba8edb https://pubmed.ncbi.nlm.nih.gov/31089504 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6ad95718cd1b211b7a303f3077ba8edb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25087576 |
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