Materno-fetal transmission of human coronaviruses: a prospective pilot study
| العنوان: | Materno-fetal transmission of human coronaviruses: a prospective pilot study |
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| المؤلفون: | Y. Laurent, Christopher Payan, S. Audebert, S. Vallet, M. C. Legrand-Quillien, M. Collet, E. Dirson, Arnaud Gagneur, Jacques Sizun, Emmanuel Oger |
| المساهمون: | CHRU de Brest - Département de Pédiatrie (CHU BREST Pédiatrie), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Laboratoire Universitaire de Biodiversité et Ecologie Microbienne (LUBEM), Université de Brest (UBO), Service de Gynécologie-Obstétrique (BREST - Gynéco-Obs), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| المصدر: | European Journal of Clinical Microbiology and Infectious Diseases European Journal of Clinical Microbiology and Infectious Diseases, Springer Verlag, 2008, 27 (9), pp.863-6. ⟨10.1007/s10096-008-0505-7⟩ European Journal of Clinical Microbiology & Infectious Diseases |
| بيانات النشر: | HAL CCSD, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | MESH: Chi-Square Distribution, MESH: Coronavirus Infections, Pilot Projects, Severe Acute Respiratory Syndrome, law.invention, Coronavirus OC43, Human, 0302 clinical medicine, law, Coronavirus 229E, Human, MESH: Reverse Transcriptase Polymerase Chain Reaction, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, MESH: Coronavirus OC43, Human, Infectious disease transmission, Obstetrics, Reverse Transcriptase Polymerase Chain Reaction, MESH: Infant, Newborn, virus diseases, General Medicine, MESH: Coronavirus 229E, Human, Concise Article, 3. Good health, MESH: Infectious Disease Transmission, Vertical, Infectious Diseases, Transmission (mechanics), MESH: Young Adult, Vagina, MESH: Nasal Mucosa, Female, Vaginal Swab, Coronavirus Infections, Microbiology (medical), Adult, medicine.medical_specialty, Infectious Bronchitis Virus, 03 medical and health sciences, Young Adult, 030225 pediatrics, MESH: Analysis of Variance, medicine, Coronavirus 229E, Humans, Fetus, Analysis of Variance, Chi-Square Distribution, MESH: Humans, business.industry, Infant, Newborn, MESH: Adult, MESH: Pilot Projects, Infant newborn, Virology, Infectious Disease Transmission, Vertical, Neonatal Infection, MESH: Prospective Studies, Neonatal infection, Nasal Mucosa, MESH: Vagina, business, MESH: Female, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| الوصف: | International audience; This prospective pilot study investigates the possibility of materno-fetal transmission of human coronaviruses (HCoV) responsible for cases of neonatal infection. This vertical transmission was studied with 159 samples from mother-child couples: maternal vaginal (MV) and respiratory (MR) samples during labor; and newborn gastric sample (NG) with detection of HCoV (229E, OC-43, NL-63, HKU1) via real time RT PCR. HCoV was detected in 12 samples (229E: 11; HKU1: 1) from seven mother-child couples. For three couples, only MR tested positive (cases 1-3). For two other couples all three samples (MV, MR and NG) tested positive (cases 4 and 5). For case 6, only MV and NG tested positive. In case 7, only MV was positive. Possible vertical transmission of HCoV was hypothesized in this pilot study and requires further investigation on a larger scale. |
| اللغة: | English |
| تدمد: | 0934-9723 1435-4373 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b728abccb478ac7287cb9393302dd50 https://hal.univ-brest.fr/hal-00749719 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6b728abccb478ac7287cb9393302dd50 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 09349723 14354373 |
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