Increase of Myocardial Ischemia Time and Short-Term Prognosis of Patients with Acute Myocardial Infarction during the First COVID-19 Pandemic Wave
| العنوان: | Increase of Myocardial Ischemia Time and Short-Term Prognosis of Patients with Acute Myocardial Infarction during the First COVID-19 Pandemic Wave |
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| المؤلفون: | Romualdas Gurevičius, Jelena Celutkiene, Egle Urbonaite, Mindaugas Lizaitis, Kamile Cerlinskaite-Bajore, Ignas Badaras, Aleksandr Volodko, Romualdas Buivydas, Povilas Budrys, Vilhelmas Bajoras, Giedrius Davidavicius, Pranas Šerpytis, Aurelija Martinonyte, Rasa Visinskiene, Laurynas Dieckus, Greta Rodevic |
| المصدر: | Medicina, Vol 57, Iss 1296, p 1296 (2021) Medicina; Volume 57; Issue 12; Pages: 1296 Medicina Medicina (Lithuania), Basel : MDPI, 2021, vol. 57, iss. 12, art. no. 1296, p. [1-11] |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Medicine (General), Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, ischemia time, Article, R5-920, COVID-19, myocardial infarction, percutaneous coronary intervention, Internal medicine, Pandemic, medicine, ST segment, Humans, Myocardial infarction, cardiovascular diseases, Pandemics, Killip class, Retrospective Studies, business.industry, SARS-CoV-2, Mortality rate, Percutaneous coronary intervention, General Medicine, medicine.disease, Prognosis, Treatment Outcome, Heart failure, Communicable Disease Control, Cardiology, ST Elevation Myocardial Infarction, business |
| الوصف: | Background and objectives: early reports showed a decrease in admission rates and an increase in mortality of patients with acute myocardial infarction (AMI) during the first wave of COVID-19 pandemic. We sought to investigate whether the COVID-19 pandemic and associated lockdown had an impact on the ischemia time and prognosis of patients suffering from AMI in the settings of low COVID-19 burden. Materials and Methods: we conducted a retrospective data analysis from a tertiary center in Lithuania of 818 patients with AMI. Data were collected from 1 March to 30 June in 2020 during the peri-lockdown period (2020 group; n = 278) and compared to the same period last year (2019 group; n = 326). The primary study endpoint was all-cause mortality during 3 months of follow-up. Secondary endpoints were heart failure severity (Killip class) on admission and ischemia time in patients with acute ST segment elevation myocardial infarction (STEMI). Results: there was a reduction of 14.7% in admission rate for acute myocardial infarction (AMI) during the peri-lockdown period. The 3-month mortality rate did not differ significantly (6.9% in 2020 vs. 10.5% in 2019, p = 0.341 for STEMI patients; 5.3% in 2020 vs. 2.6% in 2019, p = 0.374 for patients with acute myocardial infarction without ST segment elevation (NSTEMI)). More STEMI patients presented with Killip IV class in 2019 (13.5% vs. 5.5%, p = 0.043, respectively). There was an increase of door-to-PCI time (54.0 [42.0–86.0] in 2019; 63.5 [48.3–97.5] in 2020, p = 0.018) and first medical contact (FMC)-to-PCI time (101.0 [82.5–120.8] in 2019; 115 [97.0–154.5] in 2020, p = 0.01) during the pandemic period. Conclusions: There was a 14.7% reduction of admissions for AMI during the first wave of COVID-19. FMC-to-PCI time increased during the peri-lockdown period, however, it did not translate into worse survival during follow-up. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1648-9144 1010-660X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf27f394de6b75592746820e5518c85 https://www.mdpi.com/1648-9144/57/12/1296 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6bf27f394de6b75592746820e5518c85 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16489144 1010660X |
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