Co-Delivery of Hydrophobic and Hydrophilic Drugs from Nanoparticle–Aptamer Bioconjugates
العنوان: | Co-Delivery of Hydrophobic and Hydrophilic Drugs from Nanoparticle–Aptamer Bioconjugates |
---|---|
المؤلفون: | Vaishali Bagalkot, Omid C. Farokhzad, Frank X. Gu, Liangfang Zhang, Aleksandar Filip Radovic-Moreno, Robert Langer, Frank Alexis, Pamela Basto, Sangyong Jon |
المصدر: | ChemMedChem. 2:1268-1271 |
بيانات النشر: | Wiley, 2007. |
سنة النشر: | 2007 |
مصطلحات موضوعية: | Male, Aptamer, Nanoparticle, Antineoplastic Agents, Adenocarcinoma, Biochemistry, Antigens present, Cell Line, Tumor, Drug Discovery, Humans, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, Pharmacology, Co delivery, biology, Extramural, Chemistry, Organic Chemistry, Prostatic Neoplasms, Aptamers, Nucleotide, Combinatorial chemistry, Microscopy, Fluorescence, Pharmaceutical Preparations, Cell culture, Nucleic acid, biology.protein, Nanoparticles, Molecular Medicine, Antibody |
الوصف: | Apromisingapplicationofnanoparticle(NP)drugdeliverysystemsisthetargeteddeliveryoftherapeuticagentsinacell-,tissue-,ordisease-specificmanner.Thisgoalmaybeachieved by the surface-modification of NPs with antibodies,nucleic acid ligands (aptamers; Apt), peptides, or small mole-cules that bind to antigens present on the target cells or tis-sues. |
تدمد: | 1860-7187 1860-7179 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0540806273eefe9c069fce7193e9bf https://doi.org/10.1002/cmdc.200700121 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....6c0540806273eefe9c069fce7193e9bf |
قاعدة البيانات: | OpenAIRE |
تدمد: | 18607187 18607179 |
---|