Comparison of three equations for estimating low‐density lipoprotein‐cholesterol in the rural northeastern region of Thailand
| العنوان: | Comparison of three equations for estimating low‐density lipoprotein‐cholesterol in the rural northeastern region of Thailand |
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| المؤلفون: | Pattara Sanchaisuriya, Sirawich Sonsok, Pongdech Sarakarn |
| المصدر: | Journal of Clinical Laboratory Analysis |
| بيانات النشر: | John Wiley and Sons Inc., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Male, Rural Population, Clinical Biochemistry, LDL‐C equation, Low density lipoprotein cholesterol, rural area, 03 medical and health sciences, Categorical analysis, 0302 clinical medicine, cardiovascular disease, Statistics, Immunology and Allergy, Humans, Research Articles, Mathematics, Aged, Direct method, Biochemistry (medical), Public Health, Environmental and Occupational Health, Hematology, Gold standard (test), Cholesterol, LDL, Middle Aged, Thailand, Continuous data, Medical Laboratory Technology, 030104 developmental biology, northeastern Thailand, 030220 oncology & carcinogenesis, Female, agreement, Research Article |
| الوصف: | Background Cardiovascular disease is the most common cause of death worldwide, and the detection of LDL‐C contributes to reducing risks. However, the LDL‐C is rarely evaluated according to the gold standard method because it is costly and time‐consuming. This study aimed to determine the agreement of LDL‐C among three equations, namely Friedewald's equation, Puavilai's equation, and Dansethakul's equation. Methods A cross‐sectional descriptive study. Results Using the data of lipid measurement from a specific group of people in the remote rural area, we found that the Thai equations have more superior agreement with direct measurement than the Friedewald equation (ICC = 0.870, 95% CI = 0.857‐0.882) when the agreement of continuous data was used for total analysis. Although the categorical analysis that gave better agreement was from Friedewald equation (K index = 0.730, 95% CI = 0.720‐0.751), the findings from this study confirmed the population‐specific use of Pauvilai's equation and Dansethakul's equation for determining the LDL‐C. Conclusion Pauvilai's equation showed better agreement with direct measurement for LDL‐C. Thus, it could be considered as an alternative for the direct method, particularly in laboratories in rural areas in Thailand. |
| اللغة: | English |
| تدمد: | 1098-2825 0887-8013 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca79203d67aa318dbf45379a02fcbb http://europepmc.org/articles/PMC7595927 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6cca79203d67aa318dbf45379a02fcbb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10982825 08878013 |
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