Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems
| العنوان: | Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems |
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| المؤلفون: | Sumin Tang, Huijiao Chen, Zhi-Xin Chen, Bo Zhang, Chaoyong Shen, Zong-Guang Zhou, Yuan Yin, Xiaonan Yin |
| المصدر: | Oncotarget |
| بيانات النشر: | Impact Journals, LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pathology, Multivariate analysis, Rectum, Neuroendocrine tumors, World Health Organization, Single Center, World health, WHO classifications, Young Adult, 03 medical and health sciences, ENETS TNM systems, 0302 clinical medicine, medicine, Humans, Grading (tumors), Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, colorectal, Rectal Neoplasms, Proportional hazards model, business.industry, General surgery, Middle Aged, Prognosis, medicine.disease, Survival Rate, Neuroendocrine Tumors, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, Female, 030211 gastroenterology & hepatology, Who criteria, Neoplasm Grading, Clinical Research Paper, business, Follow-Up Studies |
| الوصف: | // Chaoyong Shen 1, * , Yuan Yin 1, * , Huijiao Chen 2 , Sumin Tang 1 , Xiaonan Yin 1 , Zongguang Zhou 1, 3 , Bo Zhang 1 , Zhixin Chen 1 1 Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China 2 Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China 3 Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China * These authors have contributed equally to this work Correspondence to: Zongguang Zhou, email: zhou767@163.com Bo Zhang, email: hxwcwk@126.com Keywords: neuroendocrine tumors, colorectal, prognosis, WHO classifications, ENETS TNM systems Received: August 23, 2016 Accepted: November 08, 2016 Published: November 26, 2016 ABSTRACT Background/Aims: This study evaluated and compared the clinical and prognostic values of the grading criteria used by the World Health Organization (WHO) and the European Neuroendocrine Tumors Society (ENETS). Moreover, this work assessed the current best prognostic model for colorectal neuroendocrine tumors (CRNETs). Results: The 2010 WHO classifications and the ENETS systems can both stratify the patients into prognostic groups, although the 2010 WHO criteria is more applicable to CRNET patients. Along with tumor location, the 2010 WHO criteria are important independent prognostic parameters for CRNETs in both univariate and multivariate analyses through Cox regression ( P |
| تدمد: | 1949-2553 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce3a4dd66192aecafc826d6f652393e https://doi.org/10.18632/oncotarget.13641 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6ce3a4dd66192aecafc826d6f652393e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19492553 |
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