Current state of slc and abc transporters in the skin and their relation to sweat metabolites and skin diseases
| العنوان: | Current state of slc and abc transporters in the skin and their relation to sweat metabolites and skin diseases |
|---|---|
| المؤلفون: | Biljana Mojsoska, Håvard Jenssen, Eva Aryal, Marcus M K Hughes, Bala K. Prabhala, Elnaz Safari |
| المصدر: | Hughes, M M K, Aryal, E, Safari, E, Mojsoska, B, Jenssen, H & Prabhala, B K 2021, ' Current state of slc and abc transporters in the skin and their relation to sweat metabolites and skin diseases ', Proteomes, vol. 9, no. 2, 23 . https://doi.org/10.3390/proteomes9020023 Proteomes, Vol 9, Iss 23, p 23 (2021) Proteomes |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Nervous system, sweat metabolites, Clinical Biochemistry, KNIME, ATP-binding cassette transporter, Review, Biology, skin transporters, Microbiology, Biochemistry, SWEAT, Structural Biology, medicine, Molecular Biology, Sweat metabolites, integumentary system, Disease progression, Skin transporters, Total body, Transporter, QR1-502, Cell biology, Skin diseases, medicine.anatomical_structure, skin diseases, ABC transporters, External injury, SLC transporters, Function (biology) |
| الوصف: | With a relatively large surface area (2 m2) and 15% of total body mass, the skin forms the largest organ of the human body. The main functions of the skin include regulation of body temperature by insulation or sweating, regulation of the nervous system, regulation of water content, and protection against external injury. To perform these critical functions, the skin encodes genes for transporters responsible for the cellular trafficking of essential nutrients and metabolites to maintain cellular hemostasis. However, the knowledge on the expression, regulation, and function of these transporters is very limited and needs more work to elucidate how these transporters play a role both in disease progression and in healing. Furthermore, SLC and ABC transporters are understudied, and even less studied in skin. There are sparse reports on relation between transporters in skin and sweat metabolites. This mini review focuses on the current state of SLC and ABC transporters in the skin and their relation to sweat metabolites and skin diseases. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d35a378211b95c551838820e05ce0a0 https://findresearcher.sdu.dk:8443/ws/files/183585307/proteomes_09_00023_v2.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6d35a378211b95c551838820e05ce0a0 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |