Epidemiological Research of Microtia Combined With Congenital Heart Disease
| العنوان: | Epidemiological Research of Microtia Combined With Congenital Heart Disease |
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| المؤلفون: | Qingguo Zhang, Bingqing Wang, Qi Chen, Jintian Hu, Mengxuan Zou, Tongyu Cao |
| المصدر: | Journal of Craniofacial Surgery. 32:920-924 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Heart Defects, Congenital, Pediatrics, medicine.medical_specialty, Heart disease, Population, Goldenhar syndrome, Heart Septal Defects, Atrial, 03 medical and health sciences, CHARGE syndrome, 0302 clinical medicine, 22q11 Deletion Syndrome, Ductus arteriosus, medicine, Humans, cardiovascular diseases, 030223 otorhinolaryngology, education, Congenital Microtia, education.field_of_study, business.industry, Microtia, 030206 dentistry, General Medicine, medicine.disease, medicine.anatomical_structure, Otorhinolaryngology, Echocardiography, Etiology, Surgery, business |
| الوصف: | SUMMARY Congenital heart disease (CHD) is one of the most common combined malformations of microtia. There is currently no specific study that investigates the relationship between microtia and CHD. METHODS This study collected microtia inpatients admitted from May 1, 2015 to July 31, 2016. The diagnosis of CHD was based on patient's symptoms, past history, and echocardiography. Pearson χ2 test was used to analyze the correlation between CHD and microtia. RESULTS A total of 30 cases (3.35%) were documented with CHD, including atrial septal defect (12/40.00%), ventricular septal defect (7/23.30%), patent ductus arteriosus (2/6.70%), complex congenital heart disease (3/10.00%), combined CHD (2/6.70%) and other malformations (4/13.30%). Analysis showed no statistically significant relation between CHD and the side of affected ear or gender. CONCLUSIONS The occurrence of CHD in microtia patients was higher than that in the general population. The relationship between them was explored mainly from the etiological perspective. Microtia and CHD were often combined in syndromes such as Goldenhar syndrome, 22q11 deletion syndrome, and CHARGE syndrome. Absence of genes or abnormal embryo development associated with these syndromes leads to the occurrence of both. |
| تدمد: | 1536-3732 1049-2275 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d49937c3bccdbcefe4c4db17e569d5f https://doi.org/10.1097/scs.0000000000007296 |
| رقم الأكسشن: | edsair.doi.dedup.....6d49937c3bccdbcefe4c4db17e569d5f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15363732 10492275 |
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