Outcome after severe accidental hypothermia in the French Alps: A 10-year review

التفاصيل البيبلوغرافية
العنوان: Outcome after severe accidental hypothermia in the French Alps: A 10-year review
المؤلفون: Jean François Payen, Ibrahim Moustapha, Raphaël Briot, Pierre Bouzat, Marc Blancher, Françoise Carpentier, Julien Brun, Vincent Danel, Olivier Chavanon, Amandine Rallo, Maxime Maignan, Guillaume Debaty
المساهمون: Physiologie cardio-Respiratoire Expérimentale Théorique et Appliquée (TIMC-IMAG-PRETA), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Centre Hospitalier Universitaire [Grenoble] (CHU), Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Neuro-imagerie fonctionnelle et métabolique (ANTE-INSERM U836, équipe 5), Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Sciences Po Grenoble - Institut d'études politiques de Grenoble (IEPG), Service d'anesthésie-réanimation, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Samu 38, CHU Grenoble, Service d'accueil des urgences médicales, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Resuscitation
Resuscitation, Elsevier, 2015, 93, pp.118-123. ⟨10.1016/j.resuscitation.2015.06.013⟩
Resuscitation, 2015, 93, pp.118-123. ⟨10.1016/j.resuscitation.2015.06.013⟩
بيانات النشر: HAL CCSD, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Adult, Male, Extracorporeal Circulation, medicine.medical_specialty, Resuscitation, Poison control, Hypothermia, Environment, 030204 cardiovascular system & hematology, Emergency Nursing, Extracorporeal, Body Temperature, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, medicine, Humans, Rewarming, ComputingMilieux_MISCELLANEOUS, Aged, Retrospective Studies, Creatinine, business.industry, Hemodynamics, Shock, 030208 emergency & critical care medicine, Retrospective cohort study, Avalanches, Middle Aged, Survival Analysis, Cardiopulmonary Resuscitation, Heart Arrest, 3. Good health, Surgery, Cold Temperature, Outcome and Process Assessment, Health Care, chemistry, Anesthesia, Life support, Emergency Medicine, Etiology, Female, France, medicine.symptom, Cardiology and Cardiovascular Medicine, business
الوصف: To describe the factors associated with outcome after accidental deep hypothermia.We conducted a retrospective cohort study on patients with accidental hypothermia (core temperature28 °C) admitted to a Level I emergency room over a 10-year period.Forty-eight patients were included with a median temperature of 26 °C (range, 16.3-28 °C) on admission. The etiology of hypothermia was exposure to a cold environment (n = 27), avalanche (n = 13) or immersion in cold water (n = 8). Mean age was 47 ± 22 years, and 58% were males. Thirty-two patients had a cardiac arrest (CA): 15 patients presented unwitnessed cardiac arrest (UCA) and 17 patients presented rescue collapse (RC). Extracorporeal life support (ECLS) was implemented in 21 patients with refractory cardiac arrest and in two patients with hemodynamic instability. Overall mortality was 50%. For cardiac arrest patients, only three out of 15 patients with UCA survived at day 28, whereas eight out of 17 patients with RC survived. The cerebral performance category score was 4 for all the survivors of UCA and 1 [range, 1-2] for survivors of RC. Patients with poor outcome presented more UCA, a lower pH, a higher serum potassium, creatinine, serum sodium or lactate level as well as more severe coagulation disorders.Cardiac arrest related to rescue collapse was associated with favorable outcome. On-scene rescue collapse should prompt prolonged resuscitation and ECLS rewarming in all CA patients with deep hypothermia. Conversely, unwitnessed cardiac arrest was associated with unfavorable outcome and will likely not benefit from ECLS.
اللغة: English
تدمد: 0300-9572
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcab85723fa5fbb410a863f3cc3acbd
https://hal.archives-ouvertes.fr/hal-02070807
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....6dcab85723fa5fbb410a863f3cc3acbd
قاعدة البيانات: OpenAIRE