Protective role of zinc in the pathogenesis of respiratory diseases
| العنوان: | Protective role of zinc in the pathogenesis of respiratory diseases |
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| المؤلفون: | Rumei Luan, Dongyan Ding, Qianfei Xue, Han Li, Yujuan Wang, Junling Yang |
| المصدر: | European Journal of Clinical Nutrition. 77:427-435 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Nutrition and Dietetics, Medicine (miscellaneous) |
| الوصف: | Respiratory diseases remain a major cause of morbidity and mortality worldwide. An imbalance of zinc, an essential trace element, is associated with a variety of lung diseases. We reviewed and summarized recent research (human subjects, animal studies, in vitro studies) on zinc in respiratory diseases to explore the protective mechanism of zinc from the perspective of regulation of oxidative stress, inflammation, lipid metabolism, and apoptosis. In the lungs, zinc has anti-inflammatory, antioxidant, and antiviral effects; can inhibit cancer cell migration; can regulate lipid metabolism and immune cells; and exerts other protective effects. Our comprehensive evaluation highlights the clinical and experimental effects of zinc in the pathogenesis of respiratory diseases. Our analysis also provides insight into the clinical application of zinc-targeted therapy for respiratory diseases. |
| تدمد: | 1476-5640 0954-3007 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfc7951aeaf5ed03ce8d8527381f62d https://doi.org/10.1038/s41430-022-01191-6 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....6dfc7951aeaf5ed03ce8d8527381f62d |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14765640 09543007 |
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